Urovec Capsules: Ingredients, Uses, Benefits, Use Dosage, Side Effects, Interactions

What is Urovec?

Urovec Capsules is a combination medication in Mexico containing tetracycline, sulfamethoxazole, and phenazopyridine as active ingredients. Urovec capsule is used in the treatment of urinary tract infections such as pyelitis, pyelonephritis, urethritis, urethrotrigonitis; as a prophylactic in the pre and postoperative period and in instrumental urological examinations.

Tetracycline is an antibiotic that works by stopping the growth of bacteria. Tetracyclines probably penetrate bacterial cells by passive diffusion and inhibit bacterial growth by interfering with protein synthesis or by destroying the membrane.

Sulfamethoxazole is also an antibiotic and is effective against both gram negative and positive bacteria such as Listeria monocytogenes and E. coli. Sulfamethoxazole stops bacteria from making dihydrofolic acid.

Phenazopyridine is excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. This action helps to relieve pain, burning, urgency and frequency. The precise mechanism of action is not known.

In combination, tetracycline + sulfamethoxazole + phenazopyridine work in synergy in the Urovec capsule to treat urinary tract infections and relieve symptoms because phenazopyridine is compatible with concurrent antibiotic therapy, and its analgesic properties should improve the patient’s comfort until antibiotics can control the infection. Because of its analgesic properties, it should decrease the need for systemic analgesics and other medications.

Each capsule of Urovec contains:

  • Tetracycline: 125 mg
  • Sulfamethoxazole: 50 mg
  • Phenazopyridine 250 mg
Urovec capsules

How should Urovec Capsules be taken?

Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take this medication by mouth as directed by your doctor or healthcare provider. The dosage is based on your medical condition and response to treatment.

Drink plenty of fluids while using this medication unless your doctor tells you otherwise. For the best effect, take Urovec Capsules at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

Continue to take Urovec Capsules until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

Tell your doctor if your condition persists or worsens.

Urovec side effects

Common side effects of Urovec include:

•          Black hairy tongue

•          Diarrhea

•          Dizziness

•          Headache

•          Loss of appetite & increased thirst

•          Nausea

•          Photosensitivity

•          Sore throat

•          Sores or swelling in your rectal or genital area

•          Stomach upset

•          Swollen tongue & Trouble swallowing

•          Urinating less than usual or not at all

•          Vaginal itching or discharge

•          White patches or sores inside your mouth or on your lips

Less common side effects of Urovec include:

•          Abdominal cramps

•          Antibiotic-associated pseudomembranous colitis

•          Bulging fontanels in infants

•          Diabetes insipidus syndrome

•          Esophagitis

•          Exfoliative dermatitis

•          Increased intracranial pressure

•          Itching

•          Loss of appetite

•          Pancreatitis

•          Pericarditis

•          Pigmentation of nails

•          Pseudotumor cerebri

•          Vomiting

Serious side effects of Urovec include:

•          Brown or gray tooth discoloration

•          Changes in the amount of urine

•          Dark urine

•          Easy bruising or bleeding

•          Hearing changes (e.g., ringing in the ears, decreased hearing)

•          Muscle pain

•          New signs of infection (e.g., persistent sore throat, fever, chills)

•          Numbness or tingling of the hands or feet

•          Severe stomach or abdominal pain

•          Sunburn (sun sensitivity)

•          Unusual fatigue

•          Yellowing eyes or skin

This is not a complete list of side effects and other serious side effects may occur. Call your doctor for information and medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Urovec?

Other drugs may interact with Urovec, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Medications that may interact with Urovec include:

  • Atovaquone
  • Acitretin
  • Isotretinoin
  • Strontium
  • Digoxin
  • Kaolin pectin
  • Warfarin

Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Urovec. These products can make tetracycline less effective in treating your infection. Do not take Urovec with milk or other dairy products, unless your doctor has told you to.


Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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