Anal Ease Cream: Ingredients, Uses, How it works, Side effects

Anal Ease Creams (Anal Ese, Anal Eze, or Anal Eaze) are lidocaine or benzocaine-based desensitizing anal lubes used mainly to reduce the initial discomfort associated with anal intercourse while its lubricating properties allow for ease of penetration. It works by slightly numbing the anal region.

Many men also use Anal Ease Creams like Anal Eze or Anal Ese lube inside of condoms to help numb the penis and delay ejaculation. Although the cream has a fresh-tasting strawberry or cherry flavor, Anal Eze Creams and similar products are not recommended for oral use as they will numb your mouth. Benzocaine used in the mouth may cause a condition in which the oxygen in your body tissues can become dangerously low. This is a potentially fatal condition called methemoglobinemia. Do not use Anal Ease if you have ever had this condition.

Anal Ease lubes are latex condom safe and will not damage latex condoms. However, they do not protect an individual from sexually transmitted infections, such as chlamydia, gonorrhea, herpes, hepatitis, intestinal parasites, HIV, HPV, and syphilis. Always use latex or internal condoms during anal intercourse to reduce the risk of sexually transmitted infections.

What are the ingredients in Anal Ease creams?

A 1.5 oz Tube OF Anal Ease cream and similar products mostly contain Propylene, Glycol, Benzocaine, Carbomer 940, and Triethanolamine.

How much lidocaine is in Anal Ease creams?

Anal Ease Creams contains benzocaine, an ester local anesthetic that is safer for mucus membranes like lips and anus than lidocaine. However, similar products contain 5% Lidocaine working synergistically with essential oil formulated in a slippery gel that doubles as a lube.

How long do Anal Ease creams take to start working?

Following topical administration, Anal Ease Creams starts work within minutes. Studies have shown that the absorption of benzocaine, the major active ingredient in Anal Ease is rapid and similar through both viable and nonviable skin. The onset of action is rapid (<1 minute), and the effective duration is 5 to 10 minutes.

How to use Anal Ease creams

Lightly rub a small dab of Anal Ease in and around the anal area about 5-10 minutes in advance. Wash your hands before and after using this medicine. Follow the directions on the label or those given to you by your doctor or health care professional. Do not use this medicine more often than directed.

Use the smallest amount needed to numb the skin or relieve pain. Do not use Anal Ease on large skin areas or deep puncture wounds. Avoid using Anal Ease on skin that is raw or blistered, such as a severe burn or abrasion.

Be careful not to get any amount of Anal Ease into your nose, mouth, and especially in your eyes, because it can cause severe eye irritation. If any of the medicine does get into these areas, especially the eyes, wash it with water for at least 15 minutes and check with your doctor right away.

Anal Ease is not for long-term use. Do not use for longer than directed on the label or your doctor or health care professional. Contact your doctor or health care professional if you notice redness, itching, or swelling.

What are the side effects of Anal Ease?

Anal Ease can cause several side effects, if you notice the following, report to your doctor or health care professional as soon as possible:

•          tremor

•          tiredness

•          seizures

•          pale, gray, or blue-colored skin, lips, or nail beds

•          headache

•          fast, irregular heartbeat

•          dizziness

•          confusion

•          breathing problems

•          allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•          pain, redness, or swelling,

This list may not describe all possible side effects of Anal Ease. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."

One Comment

  1. I always have a burning sensation on my phynter after bowel movement. I have a lot I f skin tags because of previous hemorrhoids. Is it OK to use anal ease to help stop the burning?

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