Ardosons Capsules: Uses, Ingredients, Dosage, Side Effects, Interactions

Ardosons is a Mexican combination pain medicine that contains active ingredients namely: 25 mg of indomethacin, 0.75 mg of betamethasone, and 215 mg of methocarbamol per capsule. There is no FDA-approved oral combination product in the U.S. that is equivalent to Ardosons.

Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of moderate to severe pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). Indomethacin is also used to treat pain in the shoulder caused by bursitis (inflammation of a fluid-filled sac in the shoulder joint) and tendinitis (inflammation of the tissue that connects muscle to bone).

Betamethasone is a prescription medication used to treat conditions such as allergic reactions, dermatologic disease, endocrine disorders, gastrointestinal disease, hematologic disorders, neoplastic disease, ophthalmic diseases, renal diseases, rheumatic disorders, and disorders affecting the nervous system.

Methocarbamol is a muscle relaxer. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Methocarbamol is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

In combination, these three drugs work synergistically in Ardosons to treat conditions such as rheumatoid arthritis, osteoarthritis, or other types of pain. Ardosons is listed as being available in a package of 20 capsules.

How should I take Ardosons?

The recommended dose of Ardosons is one pill every 8 hours for 7 days, then taper the dose to one pill every 12 hours for 7 days, then one pill every other day for 7 days, then stop the drug.

According to the manufacturer, you have to take doses and gradually taper down over several weeks.

Week 1: Take 1 capsule every 8 hours for 7 days.

Week 2: Take 1 capsule every 12 hours for 7 days.

Week 3: Take 1 capsule every 24 hours for 7 days.

In the 4th week and beyond, it says to reduce the dosage to a maintenance dose of one capsule every 3 days as long as side effects don’t come up. With a medication such as this, it can be a bit tricky since in the US individuals generally work with a prescribing physician while taking a medication like this in the long term.

Ardosons is not a drug that is intended to be taken daily for any longer period of time, primarily because of the steroid component. If you’ve been taking Ardosons for more than a few days, you usually need to reduce your dose gradually. Stopping suddenly can cause your adrenal gland, which makes important hormones for the body, to stop working. This is known as adrenal insufficiency.

Who should not take Ardosons

Avoid taking Ardosons if you have any of these conditions:

•          an unusual or allergic reaction to indomethacin, betamethasone, or methocarbamol

•          blood clotting problems

•          breast-feeding

•          Cushing’s syndrome

•          diabetes

•          eye disease, vision problems

•          glaucoma or cataracts

•          heart problems or disease

•          high blood pressure

•          infection like chickenpox, fungus, herpes, measles, or tuberculosis

•          kidney disease

•          liver disease

•          mental problems

•          myasthenia gravis

•          osteoporosis

•          pregnant or trying to get pregnant

•          seizures

•          stomach, intestinal disease

What are the side effects of Ardosons?

Ardosons may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

•        back pain

•        constipation

•        cough

•        diarrhea

•        difficult or painful speech

•        dizziness

•        drowsiness

•        fever

•        headache

•        nausea

•        ringing in the ears

•        runny or stuffy nose

•        sore throat

•        upset stomach

•        vomiting

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment.

•        blisters

•        blurred vision or other problems with sight

•        black, blue, or green discoloration of urine

•        difficult or painful urination

•        difficulty breathing or swallowing

•        excessive tiredness

•        fast heartbeat

•        fever, rash, lymph node swelling, or facial swelling

•        flu-like symptoms

•        hives

•        hoarseness

•        itching

•        lack of energy

•        loss of appetite

•        pain in the upper right part of the stomach

•        pale skin

•        rash

•        shortness of breath or difficulty breathing

•        swelling in the abdomen, ankles, feet, or legs

•        swelling of the eyes, face, tongue, lips, throat, or hands

•        unexplained weight gain

•        unusual bleeding or bruising

•        yellowing of the skin or eyes

Ardosons may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088).

What medications may interact with Ardosons?

Ardosons can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Interactions that can make drugs less effective

Taking Ardosons while you take pyridostigmine bromide can reduce the levels of pyridostigmine bromide in your body. This may reduce the effectiveness of pyridostigmine bromide.

Combining Ardosons with alcohol may increase your risk for bleeding in your stomach or intestines. Talk to your doctor if you drink alcohol. You may need to limit how much alcohol you drink while taking this medication.

Taking Ardosons with certain drugs that also cause drowsiness raises your risk of this side effect. Examples of these drugs include:

•        Anxiety drugs, such as lorazepam, diazepam, clonazepam, or alprazolam.

•        Pain drugs, such as oxycodone, hydrocodone, tramadol, or morphine.

•        Certain antidepressants, such as amitriptyline, doxepin, and imipramine.

•        Antipsychotics, such as chlorpromazine, haloperidol, or quetiapine.

•        Herbal products, such as kava-kava or valerian root.

Warnings for people with certain health conditions

For people with heart conditions: Ardosons may increase your risk for heart attack or stroke. It may also cause higher blood pressure levels.

For people with stomach problems: Ardosons may increase your risk for swelling or bleeding in your stomach and intestines. It may also increase your risk for ulcers.

For people with kidney problems: Your kidneys may not work as well when taking Ardosons. It may damage your kidneys or lower the blood flow to your kidneys.

For people with asthma: Don’t use Ardosons if you have aspirin-sensitive asthma. It may cause a fatal allergic reaction.


Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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