Cabotrim Tablets: Uses, Dosage, Side Effects, Interactions

Cabotrim is a brand of cabergoline, a medication used to treat hyperprolactinemia (high levels of prolactin, a natural substance that helps breastfeeding women produce milk but can cause symptoms such as infertility, and sexual problems, and bone loss in women who are not breast-feeding or men).

Cabotrim belongs to a class of medications called dopamine receptor agonists. It works by decreasing the amount of prolactin in the body. It stops the brain from making and releasing the prolactin hormone from the pituitary gland. Cabotrim use is usually stopped when prolactin levels are normal for 6 months. It may be given again if symptoms of too much prolactin occur again.

How to take Cabotrim

Cabotrim comes as a tablet to take by mouth. It is usually taken with or without food two times a week. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cabergoline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of Cabotrim and gradually increase your dose, not more often than once every 4 weeks. Do not stop taking Cabotrim without talking to your doctor. Your doctor will probably decrease your dose gradually.

In case of emergency or overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

•          stuffy nose

•          fainting

•          hallucinations (seeing things or hearing voices that do not exist)

Cabotrim side effects

Cabotrim oral tablets can cause drowsiness as well as other side effects.

More common side effects

The more common side effects of Cabotrim oral tablet can include:

•          nausea

•          constipation

•          headache

•          dizziness

•          weakness or lack of energy

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following.

•          Scarring of tissues in your organs, such as your heart, lungs, and kidneys. Symptoms can include:

o          trouble breathing

o          shortness of breath

o          a cough that doesn’t go away

o          chest pain that doesn’t go away

o          stomach pain

o          swelling in your legs, ankles, or feet

•          Heart valve problems. Symptoms can include:

o          swelling in your arms, legs, hands, or feet

o          trouble breathing

o          changes in your heart rhythm

o          chest pain

o          cough

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Cabotrim may interact with other medications

Cabotrim oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Drugs you should not use with Cabotrim

Don’t take these drugs with Cabotrim. Doing so can cause dangerous effects in your body. These drugs work in the exact opposite way that Cabotrim does. This means these drugs and Cabotrim will not work well because their effects cancel each other out. Examples of these drugs include:

•          Sulpiride

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

•          Haloperidol

•          Metoclopramide

•          Olanzapine

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

•          Fibrotic disorders (scar-like tissues in the heart, lungs, or stomach), history of or

•          Heart problems (eg, heart valve disease), history of or

•          Hypertension (high blood pressure), uncontrolled—Should not be used in patients with these conditions.

•          Heart disease or

•          Lung disease or other breathing problems—Use with caution. May make these conditions worse.

•          High blood pressure, controlled or

•          High blood pressure during pregnancy or a history of— Cabotrim usually decreases blood pressure but at times it may increase blood pressure and worsen these conditions.

•          Liver disease—Use with caution. You may need a lower dose of this medicine.

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