Drugs Q & A

What is the right Farmapram dose?

What is Farmapram?

Farmapram is a brand of alprazolam (Xanax) in Mexico produced by Ifa Celtics. Farmapram contains 2mg of alprazolam, it is used for the short-term relief of symptoms of anxiety or anxiety linked with depression. Farmapram is classified as a Schedule IV controlled substance.

Farmapram works by attaching to a receptor in your brain called the GABA-A (gamma-aminobutyric acid-A) receptor. When Alprazolam binds to this receptor, it has a calming effect on the brain. For anxiety disorders, Farmapram is often prescribed because it can help relieve anxiety symptoms quickly. However, other anxiety medications and talk therapy are better long-term choices for treating anxiety because Farmapram has side effects, risk of overdose, and the potential for dependence.

These other treatments may take a few weeks to take effect though. So Farmapram and other benzodiazepines are sometimes used as a “bridge” until other treatments can have a chance to work. For treating insomnia and behavioral therapy, other medications are generally preferred over Farmapram.

How long does Farmapram last?

In comparison with other benzodiazepines, the body absorbs Farmapram quickly, so its effects come on rapidly. Within about 1–2 hours, the concentration of Farmapram in the blood reaches its peak.

The effects of the drug usually appear within 1 hour, with one small-scale study finding an average onset time of 49 minutes with oral administration.

Farmapram also leaves the body quickly. Its half-life is 11.2 hours in healthy adults, meaning that the body removes about half of the Farmapram that it has absorbed in just over 11 hours.

Doctors often prescribe Farmapram take three times per day, spread out over the course of the day.

How should I take Farmapram?

Farmapram comes as a 2mg tablet, to take by mouth. The tablet is usually taken two to four times a day. The recommended dose of Farmapram is 1 tablet taken 3 times daily or as directed by your doctor. The maximum dose of Farmapram for generalized anxiety disorder is 4mg or two tablets a day in divided doses.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take alprazolam exactly as directed.

Older adults and people with advanced liver failure may require lower dosages of Farmapram, as their bodies can be more sensitive to the effects of benzodiazepines.

Doctors aim to prescribe the lowest effective dosage for the shortest duration to manage the risk of dependence.

People who take too much Farmapram may experience:

•          drowsiness

•          poor coordination

•          blurred vision

•          confusion

Sometimes, people may experience delayed symptoms, while others may experience severe symptoms, such as coma or even death.

Mixing Farmapram with other medications, alcohol, or both can cause an overdose. Sometimes, overdose is unintentional, but some people may use Farmapram alone or with other substances to intentionally harm themselves.

People often misuse Farmapram for the fast-acting, relaxed “high” it can provide. According to the Treatment Episode Data Set, the number of people seeking treatment for benzodiazepine misuse almost tripled from 1998–2008. Long-term misuse and addiction to Farmapram are associated with depression, psychotic experiences, and aggressive or impulsive behavior.

According to the Substance Abuse and Mental Health Services Administration, in 2011, there were over 1.2 million emergency room (ER) visits related to the nonmedical use of prescription drugs. Alprazolam was involved in around 10% of those visits.

The number of ER visits involving the nonmedical use of Alprazolam doubled from 57,419 to 124,902 during 2005–2010 and remained stable at 123,744 in 2011.

The most common drug combinations that healthcare professionals encountered in people presenting to ER were Farmapram with alcohol and Farmapram with prescription opiates such as hydrocodone (Zohydro ER) and oxycodone (OxyContin).

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.

What are the side effects of Farmapram?

Farmapram may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

•          changes in appetite

•          changes in sex drive or ability

•          constipation

•          difficulty concentrating

•          difficulty urinating

•          dizziness

•          drowsiness

•          dry mouth

•          headache

•          increased salivation

•          irritability

•          joint pain

•          light-headedness

•          nausea

•          talkativeness

•          tiredness

•          weight changes

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

•          confusion

•          problems with coordination or balance

•          problems with speech

•          seizures

•          severe skin rash

•          shortness of breath

•          yellowing of the skin or eyes

Farmapram may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Farmapram Interactions

•          Do not use this Farmapram if you are also using ketoconazole or itraconazole.

•          Some foods and medicines can affect how Farmapram works. Tell your doctor if you are using any of the following: Amiodarone, carbamazepine, clarithromycin, cimetidine, cyclosporine, desipramine, diltiazem, ergotamine, erythromycin, fluconazole, fluoxetine, fluvoxamine, imipramine, isoniazid, nefazodone, nicardipine, nifedipine, paroxetine, propoxyphene, sertraline, or theophyllineBirth control pillsSeizure medicine

•          Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

•          Do not drink alcohol while you are using Farmapram.

•          Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

•          Do not stop using Farmapram suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

•          Keep all medicine out of the reach of children. Never share your medicine with anyone.

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Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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