Terramycin Eye Ointment For Humans: Dosage, Side Effects, Warnings

What is Terramycin Eye Ointment used for?

Terramycin Eye Ointment is specifically designed for the treatment of superficial eye infections, primarily those induced by bacteria. These infections typically affect the outer layers of the eye, such as the conjunctiva or the cornea. Terramycin combines two potent antibiotics, oxytetracycline and polymyxin B, which act synergistically to combat the bacterial culprits behind the eye infection.

This medication contains active ingredients that can effectively fight these infections. Oxytetracycline, belonging to the tetracycline antibiotics group, plays a crucial role in inhibiting bacterial growth, while polymyxin B aids in eliminating bacteria. By understanding these components and their targeted approach, individuals can use Terramycin Eye Ointment with confidence to treat superficial eye infections and promote a swift recovery while under medical guidance.

Before Using Terramycin:

•        Allergies: Do not use Terramycin if you have had an allergic reaction to oxytetracycline, polymyxin B, or any of the other ingredients in the ointment.

•        Pregnancy and Lactation: The safety of topical tetracyclines during pregnancy is uncertain. Consult your doctor to weigh the potential benefits and risks if you are pregnant or nursing.

Before Starting to Use Terramycin:

•        Consult Your Doctor: It’s important to check with your doctor before using Terramycin, especially if you have any underlying health conditions or concerns.

•        Other Medications: Inform your doctor of any other medications you are taking, including over-the-counter products, as there are no known interactions between Terramycin and other medicines.

How to Use Terramycin:

•        Dosage: Follow your doctor’s or pharmacist’s instructions carefully. Typically, you’ll apply a small amount of the ointment (approximately 1 cm) of the ointment into the lower eyelid.

•        Frequency: Use the ointment 4 to 6 times daily or as directed by your healthcare provider.

•        Duration: Continue using Terramycin until the infection is cleared and healing is complete, or as long as your doctor recommends. The duration may vary based on the infection’s nature and severity.

•        Missed Dose: Consult your doctor or pharmacist if you forget to use Terramycin.

•        Overdose: In case of suspected overdose, seek immediate medical attention. Although there are no known cases of overdosage, it’s important to act promptly if you believe you’ve applied too much.

While Using Terramycin:

•        Communication: Inform all healthcare professionals treating you that you are using Terramycin.

•        Pregnancy: Notify your doctor immediately if you become pregnant while using this medication.

•        New Infections: Inform your doctor if new infections appear during the treatment because oxytetracycline may lead to the overgrowth of other infections, including fungi.

•        Contamination: Be careful not to contaminate the tip of the ointment tube when applying the medication.

Things You Must Not Do:

1.      Discontinuation without Doctor’s Advice: Do not discontinue using Terramycin Eye Ointment unless your doctor advises you to do so. Completing the prescribed treatment regimen is crucial to ensure the infection is fully resolved.

2.      New Medications: Do not initiate any new medications without consulting your doctor or pharmacist. They can provide guidance on potential interactions or any adverse effects related to combining medications.

3.      Sharing Medication: Under no circumstances should you give Terramycin to someone else, even if they exhibit similar symptoms or conditions as you. Medications are tailored to individual needs and should be prescribed and used accordingly.

Things to Be Careful Of:

When it comes to driving and using machinery, oxytetracycline topical preparations are not likely to impair your ability to operate vehicles or equipment. However, the direct application of Terramycin ointment in the eye may temporarily affect your vision sharpness. Therefore, it’s advisable to exercise caution and avoid activities requiring optimal vision during this period.

Side Effects

Terramycin, like all medicines, has the potential to cause side effects, although not everyone may experience them. If you notice any of the following, it’s essential to contact your doctor or pharmacist immediately:

•        Allergic Reactions: Report any signs of allergic reactions, such as rash, itching, or swelling, to your healthcare provider.

•        Burning Sensation: If you experience a burning sensation in the eye after applying the ointment, consult a medical professional.

•        Overproduction of Tears: Notify your doctor about excessive tearing as it may be a side effect.

•        Contact Dermatitis: If you develop red, sore, or inflamed skin after direct contact with the medicine, seek medical advice.

        Eye Pain: Any persistent eye pain should be reported to your healthcare provider.

•        Grittiness or Discomfort: Inform your doctor if you have a persistent feeling of grittiness or discomfort in the eye.

It’s important to note that tetracyclines, when given as tablets during tooth development (in the last half of pregnancy, infancy, and childhood up to the age of 8 years), may lead to permanent tooth discoloration and underdeveloped tooth enamel and skeleton. While the topical application of tetracyclines in Terramycin involves lower doses and is less likely to cause such effects, it’s crucial to consider the possibility and consult your healthcare provider if you have any concerns.

To report adverse effects or side effects related to Terramycin Eye Ointment to the U.S. Food and Drug Administration (FDA), you can follow these steps:

1.      Visit the FDA’s MedWatch Program Website: Go to the official MedWatch Program website, which is the FDA’s safety information and adverse event reporting program.

2.      Access the Online Reporting Form: On the MedWatch website, you can find a link to the online reporting form. It is typically labeled “Report a Problem” or “Submit Voluntary Report.” Click on this link to access the reporting form.

3.      Complete the Reporting Form: Fill out the required information on the reporting form. You will need to provide details about the adverse effects you experienced from using Terramycin Eye Ointment, as well as your personal information.

4.      Submit the Report: Once you have completed the form, review the information to ensure accuracy. Then, submit the report electronically through the MedWatch Program website.

5.      Follow Up if Necessary: After submitting the report, you may receive further communication from the FDA if they require more information or clarification about the adverse effects you reported.

6.      Keep Records: It’s a good practice to keep a record of the report you submitted and any correspondence with the FDA regarding your adverse effects.

Reporting adverse effects to the FDA through the MedWatch Program is essential for monitoring medication safety and ensuring that potential issues are investigated and addressed. Your report can contribute to the collective knowledge about the safety of medications, including Terramycin Eye Ointment, and help protect public health.

Proper Storage and Disposal of Terramycin Eye Ointment

Proper storage and disposal of Terramycin Eye Ointment are crucial for ensuring the medication’s effectiveness and minimizing environmental impact. To store it safely, always keep Terramycin Eye Ointment out of the reach and sight of children, as it’s essential to prevent unintentional ingestion.

Ensure that the medication is stored below 30°C to maintain its stability and potency. When it comes to disposal, it’s of utmost importance not to discard medicines, including Terramycin Eye Ointment, through wastewater or household waste, as this can have adverse ecological consequences. Instead, consult your pharmacist for guidance on the appropriate and eco-friendly disposal methods for medicines that are no longer required.

These responsible disposal measures play a significant role in safeguarding our environment by preventing pharmaceutical substances from entering water systems and ecosystems.


Christiana Gobina (BPharm)

Pharmacist Christiana holds a Bachelor of Pharmacy degree (BPharm) from the University of Ilorin. She is a dedicated healthcare professional with passion for Pharmacovigilance and medication safety particularly in underserved communities.

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