General Warnings

What Is A Drug Injury: Types and List of Medications

What Is a Drug Injury?

A drug injury is defined as any injury, harm or death that occurs as a result of taking prescription medication or over-the-counter drugs. The injury sustained can be a condition brought on by a serious reaction, side effect, or even death. Before any medication ever reaches the market for sale, it must be approved by the Food and Drug Administration (FDA).

However, sometimes defective medicines find their way through the system, reach the masses, and harm hundreds of people. Other times, the issue lies in the hands of improper or unclear warning labels or instructions that later cause harm. It’s also possible that the incident causing injury occurred at the pharmacy: medications were improperly handled, bottles were mislabeled, and so on. To be eligible for a drug injury case, the injury sustained must have been a preventable injury had someone such as a drug manufacturer, physician, or pharmacist made a better move.

List Of Medications And Chemicals That Can Cause Liver Injury

Toxic liver disease is damage to your liver. It’s also called hepatotoxicity or toxic hepatitis. It can cause serious symptoms or liver damage if you don’t get help. Medications, herbal supplements, chemicals, solvents, and alcohol are all possible causes of hepatotoxicity.

Drugs That Can Damage the Liver

Type of DrugExamples
AntibioticsAmoxicillin/clavulanate Clindamycin Erythromycin Nitrofurantoin Rifampin Sulfonamides Tetracyclines Trimethoprim/sulfamethoxazole Drugs used to treat tuberculosis (isoniazid and pyrazinamide)
AnticonvulsantsCarbamazepine Phenobarbital Phenytoin Valproate
AntidepressantsBupropion Fluoxetine Mirtazapine Paroxetine Sertraline Trazodone Tricyclic antidepressants such as amitriptyline
Antifungal drugsKetoconazole Terbinafine
Antihypertensive drugs (used to treat high blood pressure or sometimes kidney or heart disorders)Captopril Enalapril Irbesartan Lisinopril Losartan Verapamil
Antipsychotic drugsPhenothiazines such as chlorpromazine Risperidone
Heart drugsAmiodarone Clopidogrel
Hormones and related drugsAnabolic steroids Birth control pills (oral contraceptives) Estrogens
Pain relieversAcetaminophen NSAIDs
Other drugsAcarbose (used to treat diabetes) Allopurinol (used to treat gout) ART drugs (used to treat HIV infection) Baclofen (a muscle relaxant) Cyproheptadine (an antihistamine) Azathioprine (used to prevent rejection of an organ transplant) Methotrexate (used to treat cancer) Omeprazole (used to treat gastroesophageal reflux) PD-1/PD-L1 inhibitors (anticancer drugs) Statins (used to treat high cholesterol levels) Many types of chemotherapy, including immune checkpoint inhibitors
Medicinal herbsGermander Green tea extract Kava Energy drinks
ART = antiretroviral therapy; HIV = human immunodeficiency virus; NSAID = nonsteroidal anti-inflammatory drug.

Medicines That Can Cause Acute Kidney Injury

Many medicines can cause acute kidney injury (which used to be called acute renal failure), such as:

Antibiotics. These include aminoglycosides, cephalosporins, amphotericin B, bacitracin, and vancomycin.

Some blood pressure medicines. One example is ACE inhibitors, such as lisinopril and ramipril. Another is angiotensin receptor blockers. These include candesartan and valsartan.

Medicines used for cancer treatment (chemotherapy). Examples are cisplatin, carboplatin, and methotrexate.

Dyes (contrast media). These are used in medical imaging tests.

Illegal drugs. Examples are heroin and methamphetamine.

Medicines used to treat HIV. They are called protease inhibitors. Examples are indinavir and ritonavir.

Non-steroidal anti-inflammatory drugs. These include ibuprofen, ketoprofen, and naproxen.

Ulcer medicines. One example is cimetidine.

Be safe with medicines, always read and follow all instructions on the label. Make sure every doctor you see knows about all of the medicines, vitamins, or natural health products you take. This means anything you take with or without a prescription.


Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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