Medicines

Mucovibrol C: Uses, How it Works, Benefits, Dosage, Side Effects, Warnings

Mucovibrol C is a combination medication that contains clenbuterol and ambroxol as active ingredients to provide comprehensive treatment for respiratory conditions.

How it works

1.      Ambroxol’s Secretolytic and Surfactant-Stimulating Action: Ambroxol is a mucolytic agent that works by reducing the viscosity of mucus in the respiratory tract. It accomplishes this by breaking down complex mucus molecules, making them easier to clear from the airways. Additionally, Ambroxol stimulates the synthesis and release of alveolar and bronchiolar surfactants. These surfactants help maintain the elasticity of lung tissue, reduce surface tension, and enhance the efficiency of gas exchange in the lungs. This action aids in keeping the airways open and facilitating easier breathing.

2.      Clenbuterol’s Bronchodilator and Prophylactic Actions: Clenbuterol is a bronchodilator that relaxes the smooth muscles in the airways. This relaxation widens the bronchi and bronchioles, reducing airway constriction and making it easier to breathe. Additionally, Clenbuterol has prophylactic properties, meaning it can help prevent or reduce bronchospasm, which is the sudden and severe narrowing of the airways. This dual action of Clenbuterol promotes increased airflow and alleviates bronchial constriction.

These two active ingredients work in synergy to produce a stronger therapeutic effect.

Therapeutic Indications

Mucovibrol C is indicated for various respiratory conditions characterized by bronchospasm and the retention of secretions, including:

•        Bronchial Asthma: Alleviating bronchospasm and improving airflow in individuals with asthma.

•        Asthmatic Bronchitis: Treating inflammation and constriction of the airways in cases of bronchitis with an asthmatic component.

•        Acute Bronchitis: Providing relief from symptoms such as cough, mucus production, and bronchial constriction in acute bronchitis.

•        Chronic Bronchitis: Managing chronic inflammation and bronchial constriction associated with chronic bronchitis.

•        Spasmodic Bronchitis: Addressing bronchial spasms that cause respiratory distress.

•        Other Respiratory Tract Conditions: Helping individuals with respiratory conditions that involve bronchospasm and excessive mucus secretion.

Dosage of Mucovibrol C

The dosage of Mucovibrol C can vary based on age, weight, and the specific product used. Common dosages include:

•        For adults and children over 12 years, the typical dosage of Mucovibrol C is 3-4 teaspoons (7.5/0.015 mg-10/0.02 mg) taken 2-3 times a day.

•        Dosages for children are adjusted based on age and weight, with pediatric drops available for precise dosing.

Contraindications

Mucovibrol C should not be used in individuals who are:

•        Hypersensitive to the components of the formula.

•        Have aortic subvalvular stenosis.

•        Suffer from thyrotoxicosis.

•        Experience tachyarrhythmias.

•        Are pregnant.

Warnings and Precautions

Additional precautions and warnings include avoiding the use of Mucovibrol C shortly after a recent acute myocardial infarction (AMI). Consult with a healthcare provider for guidance in such cases.

Interactions

Clenbuterol’s action can be counteracted by beta-blockers, and the opposite interaction may also occur.

Pregnancy and Breastfeeding

Mucovibrol C is contraindicated during pregnancy and breastfeeding. Ambroxol is classified as category C according to the FDA, indicating potential risks during pregnancy.

Adverse Reactions

Possible adverse reactions to Mucovibrol C include restlessness, fine tremors in the fingers, or palpitations. These side effects should be reported to a healthcare provider if they occur.

It’s crucial to use Mucovibrol C as directed by a healthcare professional and to communicate any concerns or adverse reactions with your doctor. The dosages and recommendations may vary based on individual factors, so personalized guidance from a healthcare provider is essential for safe and effective use.

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Christiana Gobina (BPharm)

Pharmacist Christiana holds a Bachelor of Pharmacy degree (BPharm) from the University of Ilorin. She is a dedicated healthcare professional with passion for Pharmacovigilance and medication safety particularly in underserved communities.
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