When it comes to falsified, counterfeit, or fake medicines, their definitions depict a broad landscape -not of rolling hills and beautiful sunsets but of dark depths and raging undercurrents. Criminal activity to produce and distribute such medicines is on the increase and is putting health and lives at risk. With vast profits to be made and with punitive laws inadequate to cover the seriousness of the crime, this is an evolving area that deserves much attention and action.
It is estimated that counterfeit drugs provide approximately $75 billion in revenue annually to illegal operators and have caused more than 100,000 deaths worldwide. Beyond the economic is the more deadly menace of fake opioids laced with fentanyl, a powerful synthetic opioid that is similar to morphine but is 50 to 100 times more potent.
What is an M523 pill?
The white capsule-shaped pill that has the imprint 10/325 M523 has been identified as Acetaminophen and Oxycodone Hydrochloride 325 mg / 10 mg. Oxycodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines do not work well enough or cannot be tolerated.
Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage. Oxycodone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.
When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. M523 pill is classified as Schedule II controlled substance.
How to Spot Fake M523 pill
In their latest report on fake online pharmacies that ply their trade in the United States, the National Association of Boards of Pharmacy (NABP) found more than 1,500 new websites that it considers “Not Recommended,” and of these, 31% are offering illicit prescription drugs. Studies have shown that, poor quality medicines represent a global threat to the public health that can result in treatment ineffectiveness, drug resistance, increased morbidity and mortality rate, economic loss and problems to the healthcare system.
As a consumer, you may not have access to most of the test equipment used by regulatory bodies to verify the identity of a drug product. The following tips will serve as a guide to purchasing genuine M523 pills and help you avoid fakes;
Visual inspection as stated by the World Health Organization (WHO) (1999) still remains the first step in identifying potential fake drug irrespective of the analytical methods used. This is because such observation serves as a lead to identifying fake products even in the absence of the knowledge of the physical characteristics of a genuine drug product. You are expected to examine carefully both the package and its content before purchase or use.
Visual inspection of the Package
- Examine the package and check if it appears suspicious or different from what you previously know.
- Check if the security seal has been tampered with by looking for breaks or tears in the sealing tape and seals.
- Look for unusual fonts, font sizes, print color, and spelling errors.
- Check if the manufacturer’s address is traceable, that is, if it contains the exact location of the company and not just the country address.
- Check if the registration number (FDA number as the case is for products marketed or sold in United States) is properly printed or if it appears to be tampered with.
Visual inspection of the Dosage form
At this stage, you are meant to Check for differences in the physical appearance (color uniformity, size, shape, consistency etc.) of the drug. As stated by WHO, commonly encountered physical defects that should be looked out for in tablets include:
- Excessive powder and/or pieces of tablets at the bottom of the container (from abraded, crushed or broken tablets);
- Cracks or chips in the tablets, swelling, mottling, discolouration, fusion of tablets;
- Appearance of crystal on the walls of the container or on the tablet.
The source of the drug also determines if you are buying a fake M523 pill or not. Buying Mexican M523 pill exposes you to a lot of risk. Filling your prescription in a reputable pharmacy greatly reduces your chances of buying fake drugs while buying from illiterate and unqualified vendors who hawk drugs in buses, motor parks and in the streets increases your chances of buying fake drugs.
This is another way of identifying fake M523 pill. If the price is far cheaper than what is expected, then you have to think twice. However, this may not always be true especially for some products (fake innovator/generic brands) which may be sold at the same price as the genuine one.
Unexpected side effect
Counterfeit M523 most of the time contains substances other than the appropriate Active Pharmaceutical Ingredient (API). They may contain incorrect substances, improper dosage or hazardous substances like fentanyl which produce unusual side effects, worsening medical condition after taking it. The medication should be stopped once any of the above is noticed.
Fentanyl testing is one of the most reliable ways of telling a fake from a real M523. A new University of Maryland study found fentanyl tops the list of drugs detected in overdose patients at two Baltimore hospital emergency departments. The finding suggests that hospitals and medical systems throughout the United States consider adding fentanyl, a potent synthetic opioid linked to most fatal overdoses in Maryland, to their routine drug testing panels. That is the conclusion of researchers at the University of Maryland School of Medicine (UMSOM) and the Center for Substance Abuse Research (CESAR) at the University of Maryland, College Park. Currently, fentanyl is not routinely included in these panels nationwide. The procedure described below can help law enforcement agents and public health officials to pick out fentanyl laced powders and pills.
- Crush pill or pour powder into a clean bowl or test tube
- Add ¼ inch of clean water to the powder in the tube or bowl and mix properly
- Dip the end of the test strip into the residue for 15 seconds, remove, and lay on a clean flat surface
NOTE: If the strip does not either have one or two lines, the test is invalid.
According to the Pharmaceutical Research and Manufacturers of America, consumers who purchase medications online should avoid the following: sites that are located outside of the U.S. that do not indicate any physical address; sites that do not have a license by the relevant State Boards of Pharmacy; sites without a licensed pharmacist to answer questions; and websites that do not require a prescription.
Consumers who wish to purchase drugs over the Internet should look for websites that have the Verified Internet Pharmacy Practice Sites seal. These sites, which are created by the National Association of Boards of Pharmacy, are licensed pharmacies selling FDA-approved medications to discourage the sale of counterfeit drugs from illegitimate online sources.