Most drugs have similar effects on a person’s body regardless of sex. But scientists have recently realized that for some drugs, sex makes a significant difference. Specifically, some drugs are metabolized more slowly in women than in men.
Physiologic differences between men and women affect drug activity, including pharmacokinetics and pharmacodynamics. Pharmacokinetics in women is affected by lower body weight, slower gastrointestinal motility, less intestinal enzymatic activity, and slower glomerular filtration rate. Because of delayed gastric emptying, women may need to extend the interval between eating and taking medications that must be absorbed on an empty stomach. Other physiologic differences may affect medication dosages.
What is Metronidazole?
Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. Metronidazole capsules and tablets are used to treat infections of the reproductive system, gastrointestinal (GI) tract, skin, heart, bone, joint, lung, blood, nervous system, and other areas of the body.
Metronidazole capsules and tablets are also used to treat sexually transmitted diseases (STDs). Metronidazole extended-release (long-acting) tablets are used to treat bacterial vaginosis (an infection caused by too much of certain types of harmful bacteria in the vagina) in women.
Metronidazole injection is used to treat certain skin, blood, bone, joint, gynecologic, and abdominal (stomach area) infections caused by bacteria. It is also used to treat endocarditis (infection of the heart lining and valves), meningitis (infection of the membranes that surround the brain and spinal cord), and certain respiratory infections, including pneumonia. Metronidazole injection is also to prevent infection when used before, during, and after colorectal surgery.
Can Men Take Metronidazole?
Yes , metronidazole is a safe and effective treatment for men and women with infections that are sensitive to metronidazole. This medication works by stopping the growth of certain bacteria and parasites. This antibiotic treats only certain bacterial and parasitic infections. Metronidazole may also be used with other medications to treat certain stomach/intestinal ulcers caused by a bacteria (H. pylori).
What are the side effects of metronidazole in men?
The side effects of metronidazole in men and women are the same, they include: dizziness, headache, stomach upset, nausea, vomiting, loss of appetite, diarrhea, constipation, or metallic taste in your mouth may occur. If any of these effects last or gets worse, tell your doctor or pharmacist promptly.
This medication may cause your urine to turn darker in color. This effect is harmless and will disappear when the medication is stopped.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: signs of a new infection (such as sore throat that doesn’t go away, fever), easy bruising/bleeding, stomach/abdominal pain, painful urination.
Get medical help right away if you have any very serious side effects, including: unsteadiness, seizures, mental/mood changes (such as confusion), trouble speaking, numbness/tingling of arms/legs, eye pain, sudden vision changes, headache that is severe or doesn’t go away, stiff/painful neck.
Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.