Drugs Q & A

Can I Use an A 80 Pill (Mirtazapine) For Sleep?

Good sleep is necessary for optimal health and can affect hormone levels, mood and weight. Sleep problems, including snoring, sleep apnea, insomnia, sleep deprivation, and restless legs syndrome, are common.

A lack of sleep at night can make you cranky the next day. And over time, skimping on sleep can mess up more than just your morning mood. Studies show getting quality sleep on a regular basis can help improve all sorts of issues, from your blood sugar to your workouts.

What are sleep disorders?

Sleep disorders are a group of conditions that affect the ability to sleep well on a regular basis. Whether they are caused by a health problem or by too much stress, sleep disorders are becoming increasingly common in the United States. In fact, more than one-third of adults in the United States report getting fewer than 7 hours of sleep in a 24-hour period. More than 70 percent of high school students report getting fewer than 8 hours of sleep on weeknights.

There are many different types of sleep disorders. Some may be caused by other underlying health conditions. The most common is Insomnia which refers to the inability to fall asleep or to remain asleep. It can be caused by jet lag, stress and anxiety, hormones, or digestive problems. It may also be a symptom of another condition.

Insomnia can be problematic for your overall health and quality of life, potentially causing:

  • depression
  • difficulty concentrating
  • irritability
  • weight gain
  • impaired work or school performance

Unfortunately, insomnia is extremely common. Up to 50 percent of American adults experience it at some point in their lives.

What is A 80 Pill?

The yellow capsule shaped A 0 8 pill, also known as A 80 contains Mirtazapine 15 mg and it  is supplied by Aurobindo Pharma. Mirtazapine is used in the treatment of depression; major depressive disorder and belongs to the drug class tetracyclic antidepressants.

Can I Use an A 80 Pill For Sleep?

According to studies, Mirtazapine has been found to reduce the time it takes for a person to fall asleep, as well as reducing the duration of early, light stages of sleep and increasing deep sleep. It also slightly reduces REM sleep (dream sleep) and night-time waking and improves the continuity and overall quality of sleep.

Clinical evidence supporting the use of mirtazapine as a sleep aid

Using mirtazapine as a sleep aid has been looked in a handful of studies in healthy volunteers, and it has been shown to improve sleep. One such study simulated insomnia by subjecting participants to traffic noise and found that low-dose mirtzapine (7mg) improved both their sleep time and sleep quality considerably, compared to placebo.

While looking at the effects of the drug in healthy volunteers is helpful, it is possible that effects may differ between healthy people and those with insomnia.

Studies have looked at the use of mirtazapine in people suffering from depression but, to date, only one study has examined the use of this drug in patients already suffering with insomnia, without depression. The researchers look at two groups of people: those with both depression and insomnia, and those with only insomnia.

The authors found that low-dose mirtazapine was effective for treating insomnia in both groups, whether the patients also had depression or not. While these results are encouraging, there is still a pressing need to carry out more studies in people suffering with insomnia, to establish if there are any adverse effects from the long-term use of mirtazapine.


Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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