Medicines

Ampigrin PFC: Uses, Dosage, Side Effects, Interactions, FAQs

Ampigrin PFC is a medication indicated for the treatment of influenza caused by group A influenza viruses. It is formulated to provide a combination of therapeutic actions, including antiviral, analgesic, antipyretic, decongestant, and antihistamine effects. The specific components and their respective dosages in each capsule are as follows:

1.        Chlorphenamine Maleate (3 mg): Chlorphenamine is an antihistamine that helps alleviate symptoms associated with allergies and colds. It can provide relief from sneezing, itching, and runny nose.

2.        Amantadine Hydrochloride (50 mg): Amantadine is an antiviral medication that has been used to treat and prevent certain strains of influenza A virus. It works by inhibiting the replication of the virus inside the host cells.

3.        Paracetamol (Acetaminophen) (300 mg): Paracetamol is a common analgesic (pain reliever) and antipyretic (fever reducer). It helps reduce pain and fever associated with influenza.

The combination of these three active ingredients in Ampigrin PFC is intended to address multiple symptoms commonly experienced during influenza infections. The medication is available in capsule form, and each capsule contains the specified amounts of chlorphenamine maleate, amantadine hydrochloride, and paracetamol.

Presentation

•          1 Box: Contains 24 capsules

•          1 Bottle(s): Contains 24 capsules

Patients should follow the prescribed dosage and administration instructions provided by their healthcare professional. It’s important to note that, like any medication, Ampigrin PFC may have contraindications or potential interactions with other medications. Individuals should inform their healthcare provider about their medical history and current medications before starting this treatment.

Who should not use Ampigrin PFC

Here are the contraindications associated with Ampigrin PFC:

1.        Elderly Individuals: Ampigrin PFC should not be administered to elderly people. This demographic may be more vulnerable to certain side effects or interactions.

2.        History of Psychological Disorders or Seizures: Individuals with a history of psychological disorders or seizures should avoid the use of Ampigrin PFC. Certain components of the medication may exacerbate these conditions.

3.        Patients with Liver or Kidney Disorders: Ampigrin PFC is contraindicated in patients with liver or kidney disorders. The medication may pose a risk of further damage to these organs.

4.        Hyperthyroidism and Uncontrolled Hypertensive Patients: People with hyperthyroidism and uncontrolled hypertensive patients should not use Ampigrin PFC, as it may affect thyroid function and blood pressure.

5.        Malnourished Patients or Chronic Alcoholics: Caution is advised when administering Ampigrin PFC to malnourished patients or chronic alcoholics, as they may be more susceptible to liver damage.

6.        Pregnant or Lactating Women: Ampigrin PFC is contraindicated in pregnant or lactating women due to potential risks to the developing fetus or nursing infant.

7.        Epilepsy: Individuals with epilepsy should not use Ampigrin PFC, as it may exacerbate seizure activity.

8.        Glaucoma: The medication is contraindicated in individuals with glaucoma.

9.        Myasthenia Gravis: People with myasthenia gravis, a neuromuscular disorder, should avoid the use of Ampigrin PFC.

10.      Prostatic Hypertrophy: Ampigrin PFC is contraindicated in individuals with prostatic hypertrophy (enlarged prostate).

11.      Patients Receiving Treatment with MAO Inhibitors: Concurrent use of Ampigrin PFC with monoamine oxidase (MAO) inhibitors is contraindicated.

12.      Cerebral Atherosclerosis: Individuals with cerebral atherosclerosis should not use Ampigrin PFC, as it may worsen this vascular condition.

It is crucial for individuals to inform their healthcare providers about their complete medical history, including any existing conditions or medications, before starting Ampigrin PFC. This helps ensure patient safety and enables healthcare professionals to make informed decisions about the suitability of the medication for a particular individual. Always follow the advice and prescriptions provided by healthcare professionals.

Dosage Information for Ampigrin PFC

For adults and children over 12 years of age, the recommended dosage of Ampigrin PFC is as follows:

•          Dosage: 1 capsule every 8 hours.

•          Timing: The medication should be taken regularly, with one capsule administered every 8 hours.

•          Initiation of Treatment: For optimal effectiveness, it is recommended to start the treatment within the first 48 hours of the onset of symptoms.

•          Duration of Treatment: The recommended duration of treatment with Ampigrin PFC is a maximum of 5 days.

It’s important for individuals to adhere to the prescribed dosage and follow the recommended schedule provided by their healthcare professional. Taking the medication regularly and within the specified time intervals is crucial for achieving the desired therapeutic effects while minimizing the risk of adverse reactions.

Patients should also be aware of the specific contraindications and precautions associated with Ampigrin PFC, as outlined in previous discussions. If there are any concerns or questions regarding the dosage or suitability of the medication, individuals should consult their healthcare provider for personalized advice.

This dosage information is based on the details provided and is intended for general understanding. Individual variations may exist, and it is essential to follow the guidance of healthcare professionals for the most accurate and personalized recommendations.

Side Effects

While Ampigrin PFC can be effective in treating influenza symptoms, like any medication, it may be associated with side effects. It’s crucial for individuals to be aware of potential side effects and seek medical attention if they experience any adverse reactions. Here are some common side effects associated with the components of Ampigrin PFC:

1.        Chlorphenamine Maleate (Antihistamine):

•          Common side effects may include drowsiness, dry mouth, blurred vision, and constipation.

2.        Amantadine Hydrochloride (Antiviral):

•          Common side effects can include dizziness, nausea, insomnia, and nervousness.

3.        Paracetamol (Acetaminophen):

•          Common side effects may include nausea, vomiting, loss of appetite, and rash. Uncommonly, high doses of paracetamol can lead to liver damage, so it’s crucial to adhere to recommended dosages.

It’s important to note that not everyone will experience these side effects, and many individuals tolerate the medication well. If any of the following side effects persist or worsen, individuals should promptly inform their healthcare provider:

•          Allergic reactions (itching, swelling, severe dizziness, difficulty breathing)

•          Unusual fatigue or weakness

•          Persistent headache

•          Yellowing of the eyes or skin (indicative of potential liver issues)

•          Unusual bleeding or bruising

•          Changes in mood or behavior

This is not an exhaustive list of side effects, and individuals should refer to the medication’s package insert or consult their healthcare provider for a complete list of potential adverse reactions. Additionally, individuals should inform their healthcare provider of any pre-existing medical conditions or medications they are taking to minimize the risk of interactions or complications.

Frequently Asked Questions (FAQs) about Ampigrin PFC

1. What is Ampigrin PFC used for?

Ampigrin PFC is indicated for the treatment of influenza caused by group A influenza viruses, including subtypes H3N2, H2N2, and H1N1. It combines antiviral, analgesic, antipyretic, decongestant, and antihistamine actions to alleviate symptoms associated with the flu.

2. What are the active ingredients in Ampigrin PFC?

Each capsule of Ampigrin PFC contains Chlorphenamine maleate (3 mg), Amantadine hydrochloride (50 mg), and Paracetamol (300 mg).

3. How should Ampigrin PFC be taken?

For adults and children over 12 years of age, the recommended dosage is 1 capsule every 8 hours. Treatment should commence within the first 48 hours of symptom onset, and the duration of use should not exceed 5 days.

4. Are there any contraindications for Ampigrin PFC?

Yes, Ampigrin PFC should not be administered to elderly individuals, those with a history of psychological disorders or seizures, patients with liver or kidney disorders, hyperthyroidism, uncontrolled hypertensive patients, malnourished patients, chronic alcoholics, pregnant or lactating women, individuals with epilepsy, glaucoma, myasthenia gravis, prostatic hypertrophy, patients receiving treatment with MAO inhibitors, and those with cerebral atherosclerosis.

5. Can Ampigrin PFC cause liver damage?

In individuals with malnutrition or chronic alcoholism, there is a cautionary note about potential liver damage. It is important to use the medication with care in these populations.

6. Is Ampigrin PFC safe for the elderly?

Ampigrin PFC should be administered to individuals over 65 years of age only after medical evaluation. Older individuals may have specific health considerations that require assessment.

7. Can Ampigrin PFC cause drowsiness?

Yes, Ampigrin PFC may cause drowsiness. Individuals taking this medication are advised not to drive vehicles or operate machinery.

8. What should I do if I miss a dose of Ampigrin PFC?

If a dose is missed, it is advisable to take it as soon as remembered. However, if it is close to the next scheduled dose, the missed dose should be skipped. Doubling up on doses should be avoided.

9. Can pregnant or breastfeeding women use Ampigrin PFC?

No, Ampigrin PFC should not be administered to pregnant or breastfeeding women due to potential risks to the fetus or nursing infant.

10. Are there any potential drug interactions with Ampigrin PFC?

Specific drug interactions are not outlined in the provided information. However, individuals should inform their healthcare provider about all medications they are taking to ensure there are no potential interactions.

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Joan David-Leonhard

Joan David Leonhard is a recent Pharm.D graduate with a strong passion for the pharmaceutical industry and a particular interest in pharmaceutical media and communication. Her brief internship experience includes roles in pharmacy where she built strong patient-pharmacist relationships and a pharmaceutical media internship where she actively contributed to drug information articles, blog posts, social media engagement, and various media projects.
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