Drugs Q & A

What Are The Benefits of Tribedoce?

What is Tribedoce used for?

Tribedoce is a Mexican brand of Cyanocobalamin (vitamin B12), a man-made form of vitamin B12 used to prevent and treat low blood levels of this vitamin. Most people get enough vitamin B12 from their diet. Vitamin B12 is important to maintain the health of your metabolism, blood cells, and nerves.

Tribedoce injection is used to treat and prevent a lack of vitamin B12 that may be caused by any of the following: pernicious anemia (lack of a natural substance needed to absorb vitamin B12 from the intestine); certain diseases, infections, or medications that decrease the amount of vitamin B12 absorbed from food; or a vegan diet (strict vegetarian diet that does not allow any animal products, including dairy products and eggs).

How is Tribedoce used?

The recommended daily intake (RDI) of vitamin B12 is 6 micrograms per day. Deficiency is common, especially in people who follow a vegetarian or vegan diet.

In fact, it’s thought that up to 90% of people following these diets have a deficiency. This is because B12 is only found naturally in animal foods.

However, vegans and vegetarians are not the only ones who are deficient. Even some meat eaters don’t absorb it very well. Unlike other vitamins, the absorption of vitamin B12 depends on a protein produced in your stomach, called intrinsic factor.

Intrinsic factor binds to vitamin B12, so that you can absorb it into the blood. People who don’t produce enough intrinsic factor can become deficient.

Deficiency is particularly common in elderly people, because the ability to absorb vitamin B12 can decrease with age. Other people at risk of deficiency include those who have had intestinal surgery, including weight loss surgery. Those with diseases that affect the gut, such as Crohn’s disease or celiac disease, are also at risk

How effective are Tribedoce shots?

An untreated vitamin B12 deficiency can lead to neurological problems or pernicious anemia, which occurs when your body doesn’t have enough B12 to produce the amount of red blood cells it needs.

Vitamin B12  like Tribedoce shots are the most common way to prevent or treat a deficiency. The injections are prescribed by a doctor and given intramuscularly, or into muscle. If you are deficient in vitamin B12, then Tribedoce shots are very effective at raising your blood levels.

What are the potential benefits of Tribedoce shots?

Given the vital roles that vitamin B12 plays in your body, a deficiency can have serious health consequences. According to Healthline, the following are the potential benefits of Tribedoce shot:

Improved Brain Function

Low levels of Tribedoce (vitamin B12) have been linked to a decline in brain function. Two recent reviews found that there may be a link between low blood levels and the development of dementia. However, results have been mixed and treatment with vitamin B12 wasn’t effective at improving brain function in people with normal brain function.

Help With Depression

It’s been suggested that there may be a link between low vitamin B12 levels and depression. However, one review found that treating depression with vitamin B12 didn’t reduce the severity of symptoms. Nevertheless, it was suggested that taking the vitamin on a long-term basis could help prevent a relapse into depression. Currently, there is a lack of quality research in this area. Higher quality studies are needed to find out if there is a link between and depression.

Reduced Risk of Osteoporosis

Osteoporosis is a disease in which the loss of bone mass results in weaker bones and an increased risk of bone fractures. Interestingly, low blood levels of vitamin B12 have been linked with reduced bone mass. Therefore, it’s been suggested that taking Tribedoce may reduce your risk of osteoporosis. However, studies have provided mixed results.

Age-Related Macular Degeneration

Age-related macular degeneration is a condition that causes you to gradually lose central vision, usually in both eyes. In people aged 50 and over, adequate consumption of vitamin B12 is thought to be important for maintaining good vision and protecting against macular degeneration.

In one large study, 5,200 women received 1,000 mcg of vitamin B12 daily, as well as other B vitamins and folic acid .7 years later, the study found a 35% lower risk of age-related macular degeneration among the women who took the supplements. Although the reduction in risk can’t be attributed to vitamin B12 only, it does suggest that getting enough may be important. You can also find useful information on: Does Tribedoce Work For Weight Loss?

What are the potential side effect of Tribedoce shots?

There is no upper limit for the intake of Tribedoce because the risk of toxicity or overdose is extremely low.

However, Tribedoce shots may have other side effects.

Mild side effects and potential risks, which should be referred to a doctor if they persist or worsen, include:

•          pain, redness, or itching at the site of the injection

•          mild diarrhea

•          swelling sensation in the body

More serious side effects, which require immediate medical attention, include:

•          muscle cramps

•          irregular heartbeat

•          unusual weakness or tiredness

•          swelling of the ankles or feet

Severe reactions are very rare but require emergency intervention. These include:

•          itching and swelling of the face, throat, or tongue

•          breathing difficulties

•          severe dizziness

•          sudden vision changes

•          slurred speech

Drug interactions

Tribedoce may interact with certain medications. People must always inform their doctor about all prescription and over-the-counter drugs they are taking before receiving a B-12 shot.

Some commonly prescribed medications that may interact with Tribedoce:

•          Aspirin

•          antibiotics

•          H2 receptor antagonists

•          metformin

•          oral contraceptives

•          proton pump inhibitors

Allergy and medical conditions

Those who have allergies or medical conditions should always inform their doctor before receiving a B-12 shot.

Examples of allergies or conditions that may interact with Tribedoce shots include:

•          allergy to cyanocobalamin or cobalt

•          hypokalemia (low potassium levels)

•          kidney disease

•          polycythemia vera (a rare blood disorder)

•          Leber’s disease (an eye disease)

•          deficiencies in other nutrients, particularly folic acid and iron.


Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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