Medicines

Uribel Vs AZO: Differences and Similarities

Uribel and AZO are both medications used to relieve symptoms of urinary tract infections (UTIs), such as pain, burning, and urgency.  UTIs are common, particularly in women. According to the National Kidney Foundation, UTIs account for over 8.1 million visits to healthcare providers each year in the United States. In fact, UTIs are the second most common type of infection in the body, after respiratory infections.

It is estimated that about 50% of women will experience a UTI at some point in their lives, and some women may experience recurrent UTIs. Men can also get UTIs, but they are less common. UTIs can occur at any age, but they are most common in sexually active women and older adults.

UTIs can occur in any part of the urinary system, including the kidneys, ureters, bladder, and urethra. The most common type of UTI is a bladder infection, also known as cystitis. Symptoms of a bladder infection can include frequent urination, painful urination, and lower abdominal pain. If left untreated, a bladder infection can lead to a kidney infection, which is a more serious condition.

In this article, we shall be taking an in-depth look at the similarities and differences between Uribel and  AZO both of which are used to relieve symptoms of urinary tract infections

Active Ingredients of Uribel vs  AZO

Uribel contains four active ingredients: methenamine, sodium phosphate monobasic, phenyl salicylate, and hyoscyamine sulfate. Methenamine is an antibacterial agent that helps prevent the growth of bacteria in the urinary tract. Sodium phosphate monobasic and phenyl salicylate work to acidify the urine, which also helps prevent bacterial growth. Hyoscyamine sulfate is an antispasmodic agent that helps relax the bladder and urinary tract muscles, reducing pain and urgency.

 AZO, on the other hand, contains the active ingredient phenazopyridine. Phenazopyridine is a pain reliever that works by numbing the urinary tract. It does not have any antibacterial properties and does not treat the underlying infection.

Mechanism Of Action of Uribel vs  AZO

While both Uribel and  AZO can be effective at relieving UTI symptoms, they have different uses and mechanisms of action. Uribel is primarily used to treat UTIs and help prevent their recurrence, while  AZO is used to relieve pain and discomfort associated with UTIs. It’s important to note that neither medication should be used as a substitute for antibiotics or other treatments for the underlying infection.

Dosage Of Uribel vs  AZO

The recommended dosage of Uribel is two tablets taken orally four times daily after meals and at bedtime. However, the dosage may be adjusted by a healthcare provider based on the patient’s individual needs and medical history.

 AZO, on the other hand, contains phenazopyridine hydrochloride and is used to relieve symptoms of urinary tract pain, burning, and urgency. It does not treat the underlying cause of the symptoms and is not effective in treating urinary tract infections. The recommended dosage of  AZO is two tablets taken three times daily with or after meals. However, it is important to note that  AZO is not recommended for use for longer than two days without the advice of a healthcare provider.

It is important to follow the recommended dosing instructions for both Uribel and  AZO to ensure maximum effectiveness and minimize the risk of side effects.

Side Effects Of Uribel vs  AZO

Uribel and  AZO contain different active ingredients and may have different side effects. Here is a comparison of the potential side effects of Uribel vs  AZO.

Uribel:

•        Nausea and vomiting

•        Headache

•        Dry mouth

•        Blurred vision

•        Dizziness

•        Drowsiness

•        Confusion or disorientation

•        Stomach upset or pain

•        Urine discoloration (blue or green)

•        Skin rash or itching

 AZO:

•        Headache

•        Dizziness

•        Stomach upset or pain

•        Allergic reaction (rash, itching, swelling, trouble breathing)

•        Urine discoloration (orange or red)

•        Increased risk of liver damage with long-term use

It is important to note that not everyone will experience these side effects, and some people may have different reactions to these medications. If you experience any of these symptoms or other concerning side effects, it is important to talk to your doctor. They can help determine if these medications are right for you and if any other treatments or adjustments need to be made.

Drug interactions of  Uribel vs  AZO

Uribel and  AZO are both medications used for the treatment of urinary tract disorders, but they differ in their active ingredients and mechanisms of action. As such, they have different potential drug interactions.

Uribel contains a combination of methenamine, sodium phosphate monobasic, phenyl salicylate, methylene blue, and hyoscyamine sulfate.  AZO, on the other hand, contains the active ingredient phenazopyridine hydrochloride.

Some potential drug interactions with Uribel include:

•        Anticholinergic medications: Uribel contains hyoscyamine sulfate, which is an anticholinergic drug. Taking Uribel with other anticholinergic medications may increase the risk of side effects such as dry mouth, blurred vision, constipation, and urinary retention.

•        Urinary alkalinizing agents: Uribel contains sodium phosphate monobasic, which can increase urinary pH. Taking Uribel with other urinary alkalinizing agents may increase the risk of adverse effects such as kidney stones.

        Aspirin: Uribel contains phenyl salicylate, which is chemically similar to aspirin. Taking Uribel with aspirin may increase the risk of side effects such as bleeding and stomach ulcers.

Some potential drug interactions with  AZO include:

•        Antibiotics:  AZO may interfere with the effectiveness of antibiotics such as sulfonamides, tetracyclines, and nitrofurantoin.

•        Urinary acidifying agents:  AZO works by changing the pH of the urine to relieve pain and burning sensations during urination. Taking  AZO with other urinary acidifying agents may increase the risk of adverse effects such as kidney stones.

•        Liver enzymes:  AZO may interfere with liver enzyme tests, leading to false-positive results.

As with any medication, it is important to talk to a healthcare provider about potential drug interactions before taking Uribel,  AZO, or any other medication. They can provide guidance on the appropriate dosage and potential risks associated with these drugs.

Storage of Uribel vs  AZO

Uribel and  AZO have slightly different storage requirements.

Uribel should be stored at room temperature between 68°F to 77°F (20°C to 25°C), away from moisture and heat. It should be kept in a tightly closed container and out of reach of children.

 AZO, on the other hand, should also be stored at room temperature, but between 59°F to 86°F (15°C to 30°C). It should be kept in a dry place and protected from light.

It’s important to note that both Uribel and  AZO should be stored out of reach of children and away from pets. It’s also important to follow the specific storage instructions provided by the manufacturer to ensure the effectiveness and safety of the medication.

You may also find useful information on Cystex vs AZO

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Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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