Drugs Q & A

Can Antibiotics Cause Constipation?

An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria.

Antibiotics start to work immediately after you start taking them. However, you might not feel better for two to three days after the commencement of treatment. How quickly you get better after antibiotic treatment depends on the type of antibiotic and the nature of infection you are treating.

Antibiotic use in the United States is among the highest in the world. In fact, this class of drugs is prescribed to four-out-of-five Americans every year. They are an effective treatment and prevention for a variety of bacterial infections ranging from pneumonia to UTIs. And most of us have taken antibiotics at some point in our lives. However, the CDC estimates about 47 million antibiotic courses each year are prescribed for infections that don’t need antibiotics in U.S. doctors’ offices and emergency departments each year. That’s about 30% of all antibiotics prescribed.

What is constipation?

Constipation is a condition in which a person has uncomfortable or infrequent bowel movements. Generally, a person is considered to be constipated when bowel movements result in the passage of small amounts of hard, dry stool, usually fewer than three times a week. However, normal stool elimination may consist of having a bowel movement three times a day or three times a week; it depends on the person.

About 4 million people in the United States have frequent constipation. Constipation is the most common gastrointestinal complaint, resulting in 2.5 million doctor visits annually.

 Hard, dry stools are the result of the colon absorbing too much water. Normally, as food moves through the colon (also known as the large intestine) the colon absorbs water while forming stool (waste products). Muscle contractions then push the stool toward the rectum, and, by the time the stool reaches the rectum, most of the water has been absorbed, making the stool solid.

When the colon’s muscle contractions are slow or sluggish, the stool moves through the colon too slowly, resulting in too much water being absorbed.

Can antibiotics cause constipation?

Yes, but there rarely do so. Antibiotics are more likely to cause gas and diarrhea as a result of the alteration of the balance in the normal flora of bacteria in your large intestine.

Common digestive side effects of antibiotics may include:

•          bloating or feeling full

•          diarrhea

•          indigestion

•          loss of appetite

•          nausea

•          stomach pain or cramping

•          vomiting

Sometimes, a person needs to take antibiotics with food; other times, they need to take them on an empty stomach. A person can speak with their doctor or a pharmacist about how best to take their antibiotic. Most digestive problems go away once a person stops taking the antibiotic.

Persons with digestive side effects, such as bloody diarrhea, severe abdominal pain, or uncontrollable vomiting, should stop taking their antibiotics and immediately contact a doctor.

Antibiotics-induced constipation can be treated with an over-the-counter stool softener or other laxatives on a short-term basis if needed. However, ask your doctor or pharmacist for advice before combining any two medications.

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Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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