Omeprazole, sold under the brand names Prilosec and Losec among others, is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach. It works within 2 to 3 days, although it may take up to 4 weeks for omeprazole to work properly.
Omeprazole was first made in 1979 by Swedish AB Hässle, part of Astra AB. It was the first of the proton pump inhibitors (PPI). Astra AB, now AstraZeneca, launched it as an ulcer medicine under the name Losec in Sweden. It was first sold in the United States in 1989 under the brand name Losec.
What is Omeprazole used to treat?
Prescription omeprazole is used alone or with other medications to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older. Prescription omeprazole is used to treat damage from GERD in adults and children 1 month of age and older. Prescription omeprazole is used to allow the esophagus to heal and prevent further damage to the esophagus in adults and children 1 year of age and older with GERD. Prescription omeprazole is also used to treat conditions in which the stomach produces too much acid such as Zollinger-Ellison syndrome in adults.
In addition, prescription omeprazole is used to treat ulcers (sores in the lining of the stomach or intestine) and it is also used with other medications to treat and prevent the return of ulcers caused by a certain type of bacteria (H. pylori) in adults. Nonprescription (over-the-counter) omeprazole is used to treat frequent heartburn (heartburn that occurs at least 2 or more days a week) in adults.
What is constipation?
Constipation is a condition in which a person has uncomfortable or infrequent bowel movements. Generally, a person is considered to be constipated when bowel movements result in the passage of small amounts of hard, dry stool, usually fewer than three times a week. However, normal stool elimination may consist of having a bowel movement three times a day or three times a week; it depends on the person.
About 4 million people in the United States have frequent constipation. Constipation is the most common gastrointestinal complaint, resulting in 2.5 million doctor visits annually.
Hard, dry stools are the result of the colon absorbing too much water. Normally, as food moves through the colon (also known as the large intestine) the colon absorbs water while forming stool (waste products). Muscle contractions then push the stool toward the rectum, and, by the time the stool reaches the rectum, most of the water has been absorbed, making the stool solid.
When the colon’s muscle contractions are slow or sluggish, the stool moves through the colon too slowly, resulting in too much water being absorbed.
Does omeprazole cause constipation?
Yes, constipation is a common side effect of omeprazole. This happens because it works by blocking an enzyme in the lining of the stomach that is necessary for acid secretion, resulting in low stomach acid levels that can hinder nutrient absorption and cause digestive problems like constipation.
The good news is that if you have mild omeprazole-induced constipation, simple lifestyle changes can help manage the condition. Prevention tips include:
• Increasing your fiber intake: Fiber-rich foods, such as fruits, vegetables and whole grains, all help improve gut function. If you have bowel sensitivity, you’ll want to avoid high-fructose fruits, such as apples, pears and watermelon, which can cause gas.
• Getting more exercise: Regular exercise can help keep stool moving through the colon.
• Drinking more water: Aim for eight glasses daily, and avoid caffeine, as it can be dehydrating.
• Go when you feel like it: When you feel the urge to go, don’t wait.
When to See a Doctor About Constipation
If increasing fiber intake, exercise and hydration don’t solve the problem, your constipation may be characterized as chronic. Depending on the cause of chronic constipation, you may need physical therapy or even low-dose laxatives to treat the problem.
For chronic constipation, it’s important to meet with a professional who can help guide you to the right kind of therapy. This is especially important if you have any warning signs of disease, such as weight loss, bleeding or pain, or stools that become pencil-thin and stay that way.
All things considered, you should see a doctor if constipation or any other physical discomfort is interfering with your daily life.
