Drugs Q & A

Why Was Prevex Cream Discontinued?

Prevex HC Cream is a brand of 1% Hydrocortisone butyrate topical medication used to treat redness, swelling, itching, and discomfort of various skin conditions. Hydrocortisone is in a class of medications called corticosteroids. Hydrocortisone belongs to a class of drugs called glucocorticoids or adrenocorticoids. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Hydrocortisone is a steroid hormone that blocks certain proteins in your body. It works to decrease swelling and stop your immune system from reacting to different triggers. Hydrocortisone also affects how your body uses and stores carbohydrates, proteins, and fats and how your body balances water and electrolytes.

How is Prevex Cream used?

Prevex Cream is applied to the affected area in a thin film, not more than 2 to 3 times a day. Your doctor may also suggest to apply only 1 to 2 times a day. Take care not to get this medication in your eyes. Wash your hands after applying the medication. Do not use a non-breathing wrapping on the area where the medication has been applied unless instructed to do so by your doctor. Use this medication for a maximum of 4 weeks. If symptoms persist longer than 7 days, consult your doctor.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

In all cases, the smallest amount of topical hydrocortisone that provides relief from the skin condition should be used for the shortest possible length of time, to avoid unnecessary side effects.

Why Was Prevex Cream Discontinued?

Prevex HC 1% cream has not been discontinued. However, in Nov 2017, all pack sizes Prevex B Cream was discontinued as a result of manufacturing issues faced by the manufacturer (Glaxosmithkline Inc). Prevex B Cream contains Betamethasone valerate, a topical corticosteroid. It is also used to treat skin irritation and itch caused by skin conditions such as eczema, psoriasis, contact dermatitis, and seborrhea. It works by reducing redness, inflammation, swelling, and irritation of the skin. The Prevex protectant cream is also discontinued.

Prevex Cream side effects

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • burning feeling on the skin
  • dark red spots on the skin
  • infection
  • lack of healing of skin condition
  • painful, red, pus filled blisters in hair follicles
  • thinning of the skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • dry skin, irritation
  • unusual increased growth of hair on the face or body

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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