Pill Identifier

What is L374 White Pill Used For?

The white, capsule-shaped pill with the imprint L374 has been identified as Acetaminophen, Aspirin and Caffeine 250 mg / 250 mg / 65 mg. It is supplied by Perrigo Company.

The white L374 Pill is a pain reliever. It is used to treat mild aches and pains. This medicine may help with arthritis, colds, headache (including migraine), muscle aches, menstrual cramps, sinusitis, and toothache.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take L374 Pill?

They need to know if you have any of these conditions:

•        anemia

•        anxiety or panic attacks

•        asthma

•        bleeding problems

•        child with chickenpox, the flu, or other viral infection

•        diabetes

•        gout

•        heart disease

•        high blood pressure

•        if you often drink alcohol

•        kidney disease

•        liver disease

•        low level of vitamin K

•        lupus

•        smoke tobacco

•        stomach ulcers or other problems

•        trouble sleeping

•        an unusual or allergic reaction to acetaminophen, aspirin, caffeine, other medicines, foods, dyes, or preservatives

•        pregnant or trying to get pregnant

•        breast-feeding.

How should I take L374 Pill?

Take this medicine by mouth with a glass of water. Follow the directions on the package or prescription label. You can take this medicine with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

Overdosage: If you think you have taken too much of this medicine, contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with L374 pill?

Do not take this medicine with any of the following medications:

•        MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

•        methotrexate

•        other medicines with acetaminophen

•        probenecid

This medicine may also interact with the following medications:

•        alcohol

•        alendronate

•        bismuth subsalicylate

•        clozapine

•        flavocoxid

•        grapefruit juice

•        herbal supplements like feverfew, garlic, ginger, ginkgo biloba, horse chestnut

•        isoniazid

•        lithium

•        medicines for diabetes or glaucoma like acetazolamide, methazolamide

•        medicines for gout

•        medicines that stimulate or keep you awake

•        medicines that treat or prevent blood clots like enoxaparin, heparin, ticlopidine, warfarin

•        NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen

•        other aspirin and aspirin-like medicines

•        some cough and cold medicines like pseudoephedrine

•        varicella live vaccine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if the pain lasts more than 10 days, if it gets worse, or if there is a new or different kind of pain. Tell your doctor if you see redness or swelling. If you are treating a fever, check with your doctor if the fever lasts for more than 3 days.

Do not take Tylenol (acetaminophen) or medicines that have acetaminophen with this medicine. Too much acetaminophen can be very dangerous. Always read medicine labels carefully.

Report any possible overdose to your doctor or health care professional right away, even if there are no symptoms. The effects of extra doses may not be seen for many days.

This medicine can irritate your stomach or cause bleeding problems. Do not smoke cigarettes or drink alcohol. Do not lie down for 30 minutes after taking this medicine to prevent irritation to your throat.

If you are scheduled for any medical or dental procedure, tell your healthcare provider that you are taking this medicine. You may need to stop taking this medicine before the procedure.

Do not take this medicine close to bedtime. It may prevent you from sleeping.

This medicine may be used to treat migraines. If you take migraine medicines for 10 or more days a month, your migraines may get worse. Keep a diary of headache days and medicine use. Contact your healthcare professional if your migraine attacks occur more frequently.

What are the side effects of L374 pill?

Side effects that you should report to your doctor or health care professional as soon as possible:

•        allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

•        breathing problems

•        fast, irregular heartbeat

•        feeling faint or lightheaded, falls

•        fever or sore throat

•        pain on swallowing

•        ringing in the ears or trouble hearing

•        signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose

•        trouble passing urine or change in the amount of urine

•        unusually weak or tired

•        yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•        diarrhea

•        headache

•        nausea, vomiting

•        passing urine more often

•        trouble sleeping.

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.


Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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