Sanareo Cream: Uses, Benefits, Dosage, Side Effects, Interactions

Sanareo cream is a potent corticosteroid that is used topically to treat various skin conditions such as eczema, psoriasis, dermatitis, and other inflammatory skin conditions. Eczema is a condition in which patches of skin become inflamed, itchy, cracked, and rough. Psoriasis occurs when the immune system causes skin cells to grow faster than usual, and dead cells build up on the skin’s surface instead of falling away. While dermatitis is a general term that describes a common skin irritation. It has many causes and forms and usually involves itchy, dry skin or a rash. Or it might cause the skin to blister, ooze, crust or flake off.

Sanareo contains halobetasol propionate 0.05% as active ingredient. It is available as cream or ointments, The strength of the medication varies depending on the formulation and the condition being treated.

How it works

Sanareo cream works by reducing inflammation, itching, and redness in the affected area. When applied to the skin, the active ingredient (halobetasol propionate) binds to specific receptors in skin cells, known as glucocorticoid receptors. This binding activates a cascade of biochemical reactions that ultimately result in the suppression of the immune system and the reduction of inflammation.

In addition to its anti-inflammatory effects, halobetasol propionate also has vasoconstrictive properties, meaning that it narrows blood vessels in the skin. This can help to reduce redness and swelling in the affected area.

How to Appy Sanareo Cream

•          Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

•          Wash your hands with soap and water before and after you use this medicine.

•          Apply a thin layer of Sanareo cream to the affected area. Rub it in gently.

•          If you are applying Sanareo cream to the diaper area of a child, use only loose-fitting diapers or plastic pants. Tight-fitting diapers may cause too much medicine to be absorbed through the skin.

•          Do not cover the treated area with a bandage unless directed by your doctor.

Missed dose: Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra Sanareo cream to make up for a missed dose.

Store Sanareo cream in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

This medicine is for use on the skin only. Do not get it near your eyes, nose, mouth, underarms, or genitals. Do not use on skin areas that have cuts or scrapes. Do not apply the lotion to your nipple or areola, if you are breastfeeding. If it does get on these areas, rinse it off right away.

Sanareo cream should only be used as directed by a healthcare professional. It should not be used for more than two weeks. Prolonged use or misuse of this medication can lead to side effects such as skin thinning, discoloration, and increased risk of infection. If you experience any adverse effects, you should contact your healthcare professional immediately.

Side Effects

Sanareo cream can cause side effects, although not everyone will experience them. Some of the possible side effects of Sanareo cream include:

1.        Skin irritation: This is a common side effect and may include itching, burning, and stinging at the site of application.

2.        Skin thinning: Long-term use of Sanareo cream can lead to skin thinning, which makes it more susceptible to injury.

3.        Skin discoloration: Sanareo cream can cause skin discoloration, such as hypopigmentation (loss of color) or hyperpigmentation (excessive color).

4.        Acne: Sanareo cream may cause acne or worsen existing acne.

5.        Increased hair growth: In rare cases, Sanareo cream can cause excessive hair growth.

6.        Allergic reactions: Some people may have an allergic reaction to Sanareo cream, which can cause itching, rash, and swelling.

7.        Eye problems: If Sanareo cream comes into contact with the eyes, it can cause eye irritation and even glaucoma or cataracts if used for prolonged periods.

If you experience any of these side effects or other unusual symptoms while using Sanareo cream, it’s important to contact your healthcare provider right away.


•          Keep all medicine out of the reach of children. Never share your medicine with anyone.

•          If your symptoms do not improve within 2 weeks of treatment, or if they get worse, check with your doctor.

•          Tell your doctor if you are pregnant or breastfeeding, or if you have diabetes, Cushing syndrome, or any type of skin infection.

•          This medicine may cause the following problems: Adrenal gland problems, including Cushing syndrome Serious skin reactions, which may occur if you cover the treated skin area or use the lotion for a long timeHigh blood sugarEye or vision problems (including cataracts, glaucoma)


It is important to be aware of possible interactions of Sanareo cream with other medications, supplements, or substances to avoid any potential harmful effects.

Here are some known interactions of Sanareo cream:

1.        Other topical medications: Using other topical medications together with Sanareo cream may increase the risk of skin irritation and side effects.

2.        Systemic corticosteroids: Taking systemic corticosteroids such as prednisone while using Sanareo cream can increase the risk of side effects such as adrenal suppression.

3.        Immunosuppressants: Using Sanareo cream with other immunosuppressants such as cyclosporine may increase the risk of infections.

4.        Herbal supplements: It is important to consult with a healthcare provider before using any herbal supplements together with Sanareo cream as some supplements may interact and cause adverse effects.

5.        Vaccines: Sanareo cream may decrease the effectiveness of some vaccines, so it is important to inform your healthcare provider if you are using this medication before getting any vaccine.

6.        Alcohol: It is generally safe to consume alcohol while using Sanareo cream, but excessive alcohol consumption may increase the risk of skin irritation.

It is important to inform your healthcare provider of all medications, supplements, and substances you are using before starting Sanareo cream to avoid any potential interactions.


Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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