Drugs Q & A

Can Seroquel Make You High?

Seroquel, also known by its generic name quetiapine, is a medication that is primarily used to treat certain mental health conditions such as schizophrenia, bipolar disorder, and major depressive disorder. It belongs to a class of medications called atypical antipsychotics, which work by altering the levels of certain chemicals in the brain, such as dopamine and serotonin. While Seroquel is not typically used as a recreational drug, there have been reports of people using it to achieve a high or altered state of consciousness. In this article, we will explore the effects of Seroquel on the brain and body, the risks and side effects associated with its misuse, and the treatment options available for those who struggle with Seroquel addiction.

The Effects of Seroquel on the Brain and Body

As mentioned above, Seroquel works by altering the levels of certain chemicals in the brain, particularly dopamine, and serotonin. Dopamine is a neurotransmitter that is associated with pleasure and reward, while serotonin is a neurotransmitter that is associated with mood regulation and feelings of well-being. By altering the levels of these chemicals, Seroquel can help to alleviate symptoms of certain mental health conditions, such as hallucinations, delusions, and mood swings.

However, when Seroquel is used inappropriately or in large doses, it can have a number of side effects on the brain and body. Some of the potential effects of Seroquel misuse include:

1.        Sedation: Seroquel is known for its sedative properties, which can cause drowsiness, lethargy, and impaired cognitive function. This effect can be particularly dangerous when operating heavy machinery or driving.

2.        Weight gain: Seroquel is associated with weight gain, which can lead to obesity and other health problems.

3.        Tardive dyskinesia: Long-term use of Seroquel can lead to a condition called tardive dyskinesia, which is characterized by involuntary movements of the face, tongue, and other body parts.

4.        Diabetes: Seroquel has been linked to an increased risk of developing diabetes, particularly in individuals who have pre-existing risk factors.

5.        Cardiac effects: Seroquel can affect the heart, causing changes in blood pressure and heart rate. In rare cases, Seroquel has been linked to cardiac arrhythmias and sudden cardiac death.

6.        Sexual dysfunction: Seroquel can cause sexual dysfunction, including decreased libido and erectile dysfunction.

While some people may experience a sense of euphoria or altered state of consciousness when taking Seroquel, this is not typically the intended effect of the medication. Rather, these effects are usually a side effect of the sedative properties of the drug.

Risks and Side Effects Associated with Seroquel Misuse

When Seroquel is used inappropriately or in large doses, it can lead to a number of serious side effects and health risks. Some of the potential risks and side effects associated with Seroquel misuse include:

1.        Addiction: While Seroquel is not typically considered an addictive drug, some individuals may become psychologically dependent on the drug and feel the need to continue taking it even when it is no longer necessary or prescribed.

2.        Overdose: Taking large doses of Seroquel can lead to an overdose, which can be life-threatening. Symptoms of a Seroquel overdose can include seizures, irregular heart rate, respiratory distress, and coma.

3.        Withdrawal: Stopping Seroquel abruptly can lead to withdrawal symptoms, including insomnia, nausea, vomiting, and agitation.

4.        Cognitive impairment: Misusing Seroquel can lead to impaired cognitive function, making it difficult to concentrate, remember things, or make decisions.

5.        Psychosis: In rare cases, Seroquel misuse can trigger psychosis, which is a serious mental health condition characterized by delusions, hallucinations, and disordered thinking.

6.        Increased risk of accidents: Due to the sedative effects of Seroquel, misusing the drug can increase the risk of accidents and injuries, particularly when operating heavy machinery or driving.

7.        Legal consequences: Misusing Seroquel is illegal and can lead to legal consequences, including fines, imprisonment, and a criminal record.

It is important to note that Seroquel misuse can also exacerbate underlying mental health conditions and lead to further complications. For example, individuals with bipolar disorder may experience manic episodes when misusing Seroquel, while individuals with schizophrenia may experience increased symptoms of psychosis.

Treatment Options for Seroquel Addiction

If you or someone you know is struggling with Seroquel addiction, it is important to seek professional help as soon as possible. Treatment options for Seroquel addiction may include:

1.        Detoxification: The first step in treating Seroquel addiction is usually to undergo a period of detoxification, which involves gradually reducing the dose of the drug under medical supervision. This can help to manage withdrawal symptoms and reduce the risk of complications.

2.        Behavioral therapy: Behavioral therapy can help individuals to understand the underlying factors that contribute to their addiction and develop coping strategies to manage cravings and avoid relapse. Cognitive-behavioral therapy (CBT) is a particularly effective form of therapy for addiction.

3.        Medication-assisted treatment (MAT): In some cases, medication may be used to manage withdrawal symptoms and reduce the risk of relapse. For example, drugs such as buprenorphine or methadone may be used to manage opioid addiction, while drugs such as naltrexone may be used to manage alcohol addiction.

4.        Support groups: Support groups such as Alcoholics Anonymous (AA) or Narcotics Anonymous (NA) can provide ongoing support and encouragement to individuals in recovery.

5.        Dual diagnosis treatment: For individuals who have both a substance use disorder and a mental health condition, dual diagnosis treatment may be necessary. This involves addressing both the addiction and the underlying mental health condition simultaneously.

Conclusion

While Seroquel is not typically used as a recreational drug, it can have serious side effects and health risks when misused. Misusing Seroquel can lead to addiction, overdose, withdrawal, cognitive impairment, and legal consequences, among other complications. If you or someone you know is struggling with Seroquel addiction, it is important to seek professional help as soon as possible. Treatment options may include detoxification, behavioral therapy, medication-assisted treatment, support groups, and dual diagnosis treatment. With the right support and treatment, it is possible to overcome Seroquel addiction and achieve lasting recovery.

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Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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