Koften Syrup: Uses, Benefits, Dosage, Side Effects, Interactions

Koften Syrup is a combination cough and cold medication that contains 4 active ingredients that include Bromhexine, Guaifenesin, Menthol, and Terbutaline.

  • Bromhexine: Bromhexine is an expectorant that helps to thin and loosen mucus in the respiratory tract, making it easier to cough up.
  • Guaifenesin: Guaifenesin is another expectorant that works by increasing the volume and reducing the viscosity of respiratory tract secretions. It helps to relieve congestion and promotes productive coughing.
  • Menthol: Menthol is a natural compound with a cooling and soothing effect. It is commonly used in cough and cold medications to provide a sensation of relief and help alleviate throat irritation.
  • Terbutaline: Terbutaline is a bronchodilator that works by relaxing the muscles in the airways, thereby widening the air passages and making breathing easier. It is often used to relieve symptoms of respiratory conditions such as asthma and bronchitis.

In combination, these 3 active ingredients in Koften Syrup clear the respiratory tract, soothe throat discomfort and make coughing easier.

Koften Syrup Dosage

Koften Syrup is a prescription medication. To ensure proper usage, it is important to adhere to your doctor’s prescribed dosage and duration for this medication. Prior to usage, carefully read and follow the instructions on the label. Take the medication orally and use a measuring cup to accurately measure the dose. Before consuming, shake the bottle well. It is recommended to take Koften Syrup at a consistent time rather than with or without food.

Koften Syrup can be taken with or without meals. The dosage administered to you will depend on the severity of your condition and your response to the medication. It is important to adhere to your doctor’s instructions and continue using the medication for as long as advised. Ceasing treatment prematurely could result in a recurrence of symptoms and a potential worsening of your condition. Inform your doctor about any other medications you are currently taking, as certain interactions or unwanted side effects may occur.

Koften Syrup Side Effects

When taking Koften Syrup, there are several potential side effects that you should be aware of. The most commonly reported adverse effects include:

1.      Sweating: Some individuals may experience increased sweating while using Koften Syrup. This can range from mild to more noticeable sweating.

2.      Skin rash: In certain cases, a skin rash may develop as a reaction to the medication. It is important to monitor your skin for any unusual rashes or allergic reactions and inform your doctor if you experience such symptoms.

3.      Tremors: Tremors, which are involuntary shaking or trembling of the body, may occur as a side effect of Koften Syrup. These tremors can affect various parts of the body, such as the hands, legs, or even the entire body.

4.      Elevated heart rate: Koften Syrup may cause an increase in heart rate for some individuals. This can result in a faster heartbeat than usual. It is important to monitor your heart rate and consult your doctor if you notice any significant changes or irregularities.

5.      Nausea: Some people may experience feelings of nausea, which may be accompanied by a general discomfort in the stomach. This can range from mild queasiness to more persistent feelings of being sick.

6.      Indigestion: Indigestion, also known as dyspepsia, is another possible side effect of Koften Syrup. It can manifest as a feeling of fullness, bloating, or discomfort in the upper abdomen.

7.      Bloating: Bloating refers to the sensation of increased gas or swelling in the abdomen. It may cause discomfort and a feeling of tightness or fullness in the stomach area.

8.      Vomiting: Although less common, some individuals may experience episodes of vomiting while taking Koften Syrup. It is important to stay hydrated and seek medical advice if vomiting persists or becomes severe.

9.      Diarrhea: Diarrhea, characterized by loose or watery stools, may occur as a side effect of this medication. It is essential to maintain proper hydration and inform your doctor if diarrhea persists or worsens.

10.    Stomach discomfort: Along with the aforementioned gastrointestinal side effects, Koften Syrup can cause general stomach discomfort. This may include feelings of uneasiness, pain, or cramping in the abdominal area.

11.    Headaches: Headaches are another possible side effect. These can vary in intensity and may range from mild to moderate headaches.

It is important to note that not everyone will experience these side effects, and some individuals may have different reactions or additional side effects. Most of these side effects are typically transient and tend to subside as your body adjusts to the medication. However, if any of these side effects become severe, persistent, or concerning, it is crucial to contact your doctor for further evaluation and guidance.

Contact your doctor straight away if you are at all concerned about any of these side effects. Do not drive or perform any other tasks that need mental focus until you have fully experienced the effects of this medication, which can also make you sleepy. While using this medication, avoid consuming alcohol since it may worsen tiredness.

To ensure proper usage, it is important to adhere to your doctor’s prescribed dosage and duration for this medication. Prior to usage, carefully read and follow the instructions on the label.


When taking medications Koften Syrup, it is important to be aware of other drugs that may interact with them. Interactions can affect the effectiveness of the medications or increase the risk of side effects. Here are some drugs to avoid or use with caution while taking these medications:

1.      Monoamine oxidase inhibitors (MAOIs): MAOIs are a class of antidepressant medications. Combining MAOIs with Koften Syrup can lead to a potentially dangerous increase in blood pressure. Therefore, it is important to avoid taking MAOIs while using these medications.

2.      Beta-blockers: Beta-blockers are commonly used to treat conditions such as high blood pressure and heart-related issues. When used together with Terbutaline, a beta-agonist medication and one of the ingredients in Koften Syrup, the effects of both drugs on heart rate and blood pressure may be altered. Your doctor may need to adjust the dosage or monitor you closely if you need to take these medications together.

3.      Other cough and cold medications: It is important to avoid combining multiple cough and cold medications that contain similar active ingredients. This includes avoiding the simultaneous use of multiple products containing Bromhexine, Guaifenesin, Menthol, or Terbutaline. Using multiple medications with the same active ingredients can lead to an overdose or increase the risk of side effects.

4.      Medications that cause central nervous system (CNS) depression: Koften Syrup can have mild sedative effects. Taking other medications that cause CNS depression, such as opioid pain medications, sedatives, or tranquilizers, concurrently with these medications may enhance the sedative effects. This can lead to excessive drowsiness, respiratory depression, or other adverse effects. It is important to consult your doctor before combining these medications.

5.      Antihypertensive medications: The active ingredient Terbutaline can increase heart rate and blood pressure. If you are taking medications to lower blood pressure, such as calcium channel blockers or ACE inhibitors, there is a possibility of interactions. Your doctor may need to monitor your blood pressure more closely or adjust the dosages of these medications.

It is crucial to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. They can provide you with personalized advice and guidance based on your specific medical situation to ensure the safe and effective use of these medications.

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