Drugs Q & A

How Long Does It Take For Magnesium Citrate To Work?

Magnesium citrate is a type of magnesium supplement that combines magnesium with citric acid. It is commonly used to promote regular bowel movements and relieve constipation. When taken orally, magnesium citrate works by attracting water into the intestines and helping to soften and break up stool, making it easier to pass.

In addition to its laxative properties, magnesium citrate also plays an important role in many other bodily functions. Magnesium is an essential mineral that is involved in more than 300 biochemical reactions in the body, including muscle and nerve function, blood sugar regulation, and bone health. Magnesium citrate is available in a variety of forms, including tablets, capsules, and liquid.

How it Works

Magnesium citrate works by attracting water molecules from surrounding tissues and fluids into the intestines, which helps to soften and break up stool. This softening effect, along with increased water content in the intestines, makes it easier for stool to pass through the colon and be eliminated from the body.

Magnesium citrate also helps to relax the muscles in the intestines, which can further facilitate bowel movements. Additionally, magnesium itself is an essential mineral that plays a key role in many bodily processes, including muscle and nerve function, blood sugar regulation, and bone health.

When taken orally, magnesium citrate is absorbed into the bloodstream and transported to various parts of the body where it is needed. It can also be excreted by the kidneys if the body has an excess of magnesium.

Factors That Can Affect Magnesium Citrate’s Effectiveness

The effectiveness of magnesium citrate can vary depending on a number of factors. These factors include:

  • Age: Older adults may experience slower bowel motility, which can affect how quickly magnesium citrate works.
  • Weight: Individuals who weigh more may require a higher dosage of magnesium citrate to achieve the desired effect.
  • Health conditions: Certain health conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or diabetes, can affect bowel function and may impact how quickly magnesium citrate works.
  • Medications: Certain medications, such as opioids or anticholinergics, can cause constipation and may affect the effectiveness of magnesium citrate.
  • Dosage: The dosage of magnesium citrate can also impact how quickly it works. Higher dosages may produce a more rapid effect, but can also increase the risk of side effects.

How To Take Magnesium Citrate For Best Results

Here are some tips on how to take magnesium citrate for best results:

1.        Follow the instructions on the label: The dosage and frequency of magnesium citrate can vary depending on the product, so it is important to follow the instructions on the label. Do not take more than the recommended amount without consulting a healthcare provider.

2.        Take on an empty stomach: Magnesium citrate is best absorbed when taken on an empty stomach. Try taking it first thing in the morning or several hours after your last meal.

3.        Mix with water: Magnesium citrate is available in liquid form or as a powder that can be mixed with water. Mix the supplement with a small amount of water and drink it quickly. You may want to have a glass of water nearby to chase it down.

4.        Stay hydrated: Magnesium citrate can cause dehydration, so it is important to drink plenty of water before and after taking the supplement. This can also help to promote bowel movements.

5.        Be patient: Magnesium citrate can take several hours to work, so be patient and wait for the effects to take place. Avoid taking it right before bedtime, as it can cause discomfort during the night.

It is important to talk to a healthcare provider before taking magnesium citrate or any other supplement, especially if you have any underlying health conditions or are taking other medications.

How Long Does It Take for Magnesium Citrate to Work?

The time it takes for magnesium citrate to work can vary depending on the individual and the dosage of magnesium citrate that is taken. In general, magnesium citrate is known for its fast-acting properties and is typically effective at promoting bowel movements within 30 minutes to 6 hours after ingestion. However, the onset of action can depend on a number of factors, including the individual’s age, weight, and overall health, as well as the dosage of magnesium citrate that is taken.

For example, in a study published in the Journal of Gastrointestinal and Liver Diseases, researchers found that a single dose of magnesium citrate was effective at relieving constipation in 60% of participants within 4 hours of ingestion. In another study published in the Journal of Clinical Gastroenterology, researchers found that a single dose of magnesium citrate produced a bowel movement within 4 hours in 95% of participants.

The dosage of magnesium citrate can also impact how quickly it works. Higher dosages may produce a more rapid effect, but can also increase the risk of side effects such as abdominal cramping and diarrhea. The recommended dosage of magnesium citrate for constipation relief is typically 240 mL (8 ounces) of liquid magnesium citrate, which contains approximately 1.745 grams of magnesium citrate.

How Long Does Magnesium Citrate Last​?

The duration of the effects of magnesium citrate can vary depending on the individual and the reason for taking the medication. Here are some general guidelines:

For constipation relief: After taking magnesium citrate for constipation relief, you can expect to experience bowel movements within 30 minutes to 6 hours. The effects of the medication typically last for several hours, and you may continue to have loose stools or diarrhea for up to 24 hours.

For bowel preparation: Magnesium citrate is also used to prepare the bowel for medical procedures such as colonoscopy or surgery. The effects of the medication can last for up to 12 hours or more, depending on the dosage and individual response. It is important to follow the instructions provided by your healthcare provider to ensure that the medication is effective and your bowel is properly cleansed.

Overall, it is important to remember that magnesium citrate is a short-term solution for constipation relief or bowel preparation. It should not be used for extended periods of time without consulting a healthcare provider. If you experience persistent constipation or other gastrointestinal symptoms, it is important to speak with your doctor to determine the underlying cause and develop an appropriate treatment plan.

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Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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