Medicines

Mounjaro: Benefits, How to Take, Side Effects, Cost, Pancreatitis

What is Mounjaro?

Mounjaro is an injectable prescription medication containing the active ingredient tirzepatide that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) agonists. It is designed to assist adults with type 2 diabetes mellitus in managing their blood sugar levels. When combined with a proper diet and exercise regimen, Mounjaro helps improve glucose control.

During clinical trials, both with and without the concurrent use of other diabetes medications, it was observed that Mounjaro helped approximately 75% to 90% of individuals achieve an A1C level below 7%. These findings were based on the assessment of study participants who initially had A1C levels ranging from 7.9% to 8.6%. The measurements were taken at 40 and 52 weeks into the study. The effectiveness of Mounjaro was evaluated across different doses, namely 5 mg, 10 mg, and 15 mg.

Due to the potential for significant weight loss associated with Mounjaro, both individuals with and without type 2 diabetes have expressed interest in using it for weight management benefits. However, it is crucial to note that Mounjaro should only be used for weight loss under the guidance and approval of a healthcare professional.

It is worth mentioning that there has been a shortage of Mounjaro in recent months due to its increased demand and popularity. Currently, Mounjaro is listed on the Food and Drug Administration (FDA) drug shortage list, which indicates limited availability of the medication. However, it is important to note that all doses of Mounjaro are currently available despite the shortage, ensuring that individuals who require the medication for diabetes management can still access it.

If you are considering using Mounjaro for weight loss or have concerns about its availability, it is advisable to consult with your healthcare provider for personalized advice and the most up-to-date information on the medication’s usage and availability.

However, its suitability for individuals who have experienced pancreatitis remains uncertain. It’s important to note that Mounjaro is not intended for use in individuals with type 1 diabetes. Additionally, the safety and effectiveness of Mounjaro for children under the age of 18 have yet to be established.

What company manufactures Mounjaro?
Mounjaro is manufactured by Eli Lilly and Company. Its delivery device base are trademarks are owned by the company, its subsidiaries, or affiliates.

How to use Mounjaro

To properly administer Mounjaro, please follow these guidelines:

1.        Carefully read the Instructions for Use provided along with Mounjaro.

2.        Follow your healthcare provider’s instructions precisely regarding the usage of Mounjaro.

3.        Mounjaro should be injected subcutaneously, which means under the skin, into your abdomen (stomach), thigh, or upper arm.

4.        Administer Mounjaro once a week, on any day and at any time that is convenient for you.

5.        Do not mix Mounjaro with insulin in the same injection.

6.        It is acceptable to inject Mounjaro and insulin in the same general area, such as the stomach, but avoid injecting them directly adjacent to each other.

7.        Rotate your injection site each week to ensure you do not use the same site repeatedly.

8.        In case of accidental overdose or taking too much Mounjaro, promptly contact your healthcare provider or seek medical advice.

Remember, it is essential to consult with your healthcare provider and carefully follow their instructions for the appropriate use of Mounjaro.

Mounjaro Side Effects

Some of the most frequently reported side effects associated with Mounjaro usage are:

1.        Nausea

2.        Diarrhea

3.        Decreased appetite

4.        Vomiting

5.        Constipation

6.        Indigestion

7.        Stomach (abdominal) pain

If you experience any bothersome side effects or if any side effects persist and do not resolve on their own, it is recommended to discuss them with your healthcare provider. They can provide guidance and assistance in managing any adverse effects you may be experiencing.

Mounjaro may also cause serious side effects that require immediate medical attention. These include:

1.        Pancreatitis: If you experience severe and persistent stomach pain, with or without vomiting, that radiates from your abdomen to your back, discontinue the use of Mounjaro and contact your healthcare provider right away.

2.        Low blood sugar (hypoglycemia): Combining Mounjaro with other medications that can cause low blood sugar, such as sulfonylureas or insulin, may increase your risk. Symptoms of low blood sugar may include dizziness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood changes, hunger, weakness, and jitteriness.

3.        Serious allergic reactions: If you encounter signs of a severe allergic reaction, such as swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, severe rash or itching, fainting, dizziness, or rapid heartbeat, discontinue Mounjaro and seek immediate medical assistance.

4.        Kidney problems (kidney failure): Individuals with pre-existing kidney problems may experience worsened kidney function due to dehydration caused by symptoms like diarrhea, nausea, and vomiting. It is important to stay hydrated to minimize the risk of dehydration.

5.        Severe stomach problems: Some users of Mounjaro have reported severe stomach problems. If you experience persistent or severe stomach issues, inform your healthcare provider.

6.        Changes in vision: Notify your healthcare provider if you notice any changes in your vision while using Mounjaro.

7.        Gallbladder problems: There have been cases of gallbladder problems associated with Mounjaro use. Contact your healthcare provider immediately if you experience symptoms such as upper abdominal pain, fever, yellowing of the skin or eyes (jaundice), or clay-colored stools.

It is important to be aware of these potential serious side effects of Mounjaro and to promptly seek medical attention if any of these symptoms occur. Remember these are not the only possible side effects of Mounjaro.

Warnings

1.        Tumor Risks: Mounjaro has the potential to cause thyroid tumors, including thyroid cancer. It is important to be vigilant for any symptoms such as a lump or swelling in the neck, hoarseness, difficulty swallowing, or shortness of breath. If you experience any of these symptoms, inform your healthcare provider immediately.

2.        Medullary Thyroid Carcinoma (MTC): Do not use Mounjaro if you or any of your family members have a history of medullary thyroid carcinoma (MTC), which is a type of thyroid cancer.

3.        Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2): Mounjaro should not be used if you have been diagnosed with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), a hereditary disorder associated with an increased risk of developing certain types of tumors, including MTC.

4.        Allergic Reactions: If you are allergic to Mounjaro or any of its ingredients, refrain from using the medication.

It is crucial to heed these warnings and communicate any relevant medical history or concerning symptoms to your healthcare provider. They can provide appropriate guidance and determine the safest course of action for your specific situatio

What does Mounjaro cost per month?

The cost of Mounjaro without the Mounjaro Savings Card or any other discount program is $1000 per month. The Mounjaro Savings Card, offered by Eli Lilly, provides potential cost savings for individuals using Mounjaro. By utilizing this savings card, the cost of Mounjaro is limited to $150 per month or $1,800 per year, resulting in savings of approximately 85%. Eligible individuals may qualify to pay as little as $25 for a one-month or three-month supply of Mounjaro. The specifics of eligibility criteria and terms and conditions should be obtained from the program provider.

Mounjaro Online

Mounjaro availability online is not an issue as many telehealth companies offer Mounjaro for purchase online here some options you should know:

OptionBest forBranded or genericCostsAccepts insurance?
Sesame Careinsurance coveragegenericVaries by doctorYes
K Healthtype 2 diabetesgeneric– $39 for a one-time visitYes
– $488 per year for membership
PlushCarean affordable subscriptionbranded– With insurance: $14.99 per month plus copayYes
– Without insurance: $14.99 per month plus $99–$129 per appointment
Calibrateweight lossbranded– From $138 per month with Affirm insuranceYes
– $1,649 up front without insurance

Please note that the information provided here may not be exhaustive or up to date. It is always recommended to verify the specific costs and insurance acceptance with the respective healthcare providers or contact your insurance provider for accurate details regarding obtaining Mounjaro through a doctor.

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Dr. Oche Otorkpa PG Cert, MPH, PhD

Dr. Oche is a seasoned Public Health specialist who holds a post graduate certificate in Pharmacology and Therapeutics, an MPH, and a PhD both from Texila American University. He is a member of the International Society of Substance Use Professionals and a Fellow of the Royal Society for Public Health in the UK. He authored two books: "The Unseen Terrorist," published by AuthorHouse UK, and "The Night Before I Killed Addiction."
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