What is Adco-Contromet?
Adco-Contromet increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines. Adco-Contromet is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms. Adco-Contromet is also used to treat slow gastric emptying in people with diabetes, which can cause nausea, vomiting, heartburn, loss of appetite, and a feeling of fullness after meals.
How does Adco-Contromet work?
Adco-Contromet contains metoclopramide, which acts on the chemoreceptor trigger zone to produce an anti-emetic effect. It also has a peripheral action which alters upper gut motility, increasing stomach peristalsis and emptying, as well as relaxing the pyloric antrum and duodenal cap. Gastric secretion is unaffected. The direct effects on the gut are antagonized by atropine and other anticholinergics. Metoclopramide causes a marked increase in the amplitude, frequency and duration of gastric contractions. The action of
metoclopramide is not affected by vagotomy. Metoclopramide is well absorbed following oral and rectal administration.
Can I Use Adco-Contromet Syrup For Vomiting?
Adco-Contromet (metoclopramide) is a dopamine antagonist that can be used as an antiemetic (anti-vomiting) agent. Metoclopramide has been approved by the FDA specifically to treat nausea and vomiting in patients with gastroesophageal reflux disease or diabetic gastroparesis by increasing gastric motility. It is also used to control nausea and vomiting in chemotherapy patients.
Metoclopramide is a prescription medication and as a result, metoclopramide OTC (over-the-counter) is not available in the United States. Because of these regulations, one cannot simply buy metoclopramide online legally. Instead, a valid metoclopramide prescription is first needed before a pharmacy will dispense the medication.
What are the side effects of Adco-Contromet Syrup?
Adco-Contromet syrupmay cause drowsiness. Some people may have dizziness, nervousness, or headaches after they stop taking this drug. It can also cause other side effects.
More common side effects
The more common side effects of Adco-Contromet syrupcan include:
• headache
• confusion
• trouble sleeping
• dizziness
• restlessness
• sleepiness
• exhaustion
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
• Depression and suicide. Symptoms can include:
o sadness
o lack of motivation
o thoughts of harming or killing yourself
• Neuroleptic malignant syndrome (nervous system disorder). Symptoms can include:
o high fever
o stiff muscles
o trouble thinking
o fast or irregular heart rate
o increased sweating
• Tardive dyskinesia, a movement disorder that can be permanent. Symptoms can include repeated, uncontrollable movements such as:
o movement in the face, such as blinking, grimacing, or sticking out your tongue
o slow or fast, jerky movements of the arms and legs
• Parkinsonism (symptoms similar to those caused by Parkinson’s disease). Symptoms can include:
o shaking
o body stiffness
o slow movement
o trouble keeping your balance
o blank stare with an open mouth
• Allergic reaction. Symptoms can include:
o rash
o hives
o trouble breathing
o swelling of your tongue, lips, or throat
• Hyperprolactinemia (increased levels of the hormone prolactin). Symptoms can include:
o menstrual problems or vaginal dryness in women
o erectile dysfunction, decreased body hair and muscle mass, and increased breast size in men
• Hallucinations (seeing or hearing things that aren’t there)
Adco-Contromet syrup may interact with other medications
Metoclopramide oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with Adco-Contromet syrupare listed below:
Interactions that increase your risk of side effects from metoclopramide
Taking Adco-Contromet syrupwith certain medications raises your risk of side effects from Adco-Contromet syrup. Examples of these drugs include:
• Sedatives, hypnotics, narcotics, antihistamines, and tranquilizers. These include:
o diazepam
o lorazepam
o hydroxyzine
o phenobarbital
o promethazine
o scopolamine
o eszopiclone
o temazepam
o zaleplon
o zolpidem
o meperidine
o propofol
o meprobamate
Taking any of these drugs with Adco-Contromet syrupmay increase drowsiness.
• Monoamine oxidase inhibitors (MAOIs). These include:
o isocarboxazid
o phenylzine
o rasagiline
o selegiline
o tranylcypromine
Taking these drugs with Adco-Contromet syru pmay increase your blood pressure.
